NF1型恶性外周神经鞘瘤一例  

Malignant peripheral nerve sheath tumors with neurofibromatosis type 1:a case report

作　　者：祖丽胡玛尔·莫沙 布瓦杰尔·亚克亚[1] 刘建勇[1] 康晓静[1] Zulihumaer·Mosha;Buwajieer·Yakeya;LIU Jianyong;KANG Xiaojing(Department of Dermatology and Venereology,People's Hospital of Xinjiang Uygur Autonomous Region,Xinjjiang Clinical Research Center For Dermatologic Diseases,Xinjiang Key Laboratory of Dermatology Research(XJYS1707),Urumqi 830001,China)

机构地区：[1]新疆维吾尔自治区人民医院皮肤性病科,新疆皮肤病临床医学研究中心,新疆皮肤病研究重点实验室(XJYS1707),乌鲁木齐830001

出　　处：《中国麻风皮肤病杂志》2023年第4期272-274,共3页China Journal of Leprosy and Skin Diseases

摘　　要：患者,男,72岁。左下肢肿物10余年,加重1年。局部术后免疫组化:CD34阴性,CD31阴性,CD117阴性,NF阴性,Desmin阴性,SMA阴性,P53阴性,CK-Pan阴性,Ki-67大于40%,S-100阳性。结合家族史及临床表现,符合NF1型恶性外周神经鞘瘤诊断。A 72-year-old male presented with tumor on the left lower limb for more than 10 years and aggravated for 1 year.Immunohistochemical examination after local surgery showed CD34(-),CD31(-),CD117(-),NF(-),Desmin(-),SMA(-),P53(-),CK-Pan(-),Ki-67,more than 40%,S-100(+).Combined with family hitory and clinical manifestation,the diagnosis of malignant peripheral nerve sheath tumors with neurofibromatosis type 1 was macle.

关 键 词：恶性外周神经鞘瘤 1型神经纤维瘤病 

分 类 号：R739.4[医药卫生—肿瘤]