海参多糖结构表征的研究进展  

Research progress on structural characterization of sea cucumber polysaccharide

作　　者：顾兴宇 白光辉 刘璐 赵前程 李莹[1,2,3] GU Xing-yu;BAI Guang-hui;LIU Lu;ZHAO Qian-cheng;LI Ying(College of Food Science and Engineering,Dalian Ocean University,Dalian 116023,China;Open Fund of Key Laboratory of Biotechnology and Bioresources Utilization,Dalian Minzu University,Dalian 116600,China;Collaborative Innovation Center of Seafood Deep Processing,Dalian Polytechnic University,Dalian 116034,China;Key Laboratory of Aquatic Product Processing and Utilization of Liaoning Province,Dalian 116023,China)

机构地区：[1]大连海洋大学食品科学与工程学院,辽宁大连116023 [2]大连民族大学生物技术与资源利用教育部重点实验室,辽宁大连116600 [3]大连工业大学海洋食品精深加工省部共建协同创新中心,辽宁大连116034 [4]辽宁省水产品加工及综合利用重点实验室,辽宁大连116023

出　　处：《中国海洋药物》2023年第1期66-75,共10页Chinese Journal of Marine Drugs

基　　金：国家重点研发计划项目(2018YFD0901004);辽宁省科技重大专项计划项目(2020JH1/10200001);辽宁省教育厅科学研究经费项目(QL202007);大连市科技之星项目(2020RQ116);生物技术与资源利用教育部重点实验室开放课题项目(KF2022007)资助。

摘　　要：海参多糖是1种富含硫酸基团的杂多糖,结构复杂,具有多种生物活性,其生物活性与海参多糖本身的化学组成、相对分子质量、硫酸化模式等结构特征息息相关。为了更好地研究海参多糖的生物活性,全面总结海参多糖结构的分析方法,综述海参中性聚糖、海参岩藻糖基化硫酸软骨素和海参岩藻聚糖硫酸酯的结构特征,以期为海参多糖的生物活性及构效关系等后续研究提供理论基础。Sea cucumber polysaccharide is a kind of heteropolysaccharide rich in sulfate groups. It has complex structures and various biological activities. Its biological activity is closely related to its chemical composition, molecular weight, and sulfated patterns. Therefore, in order to study the biological activity of sea cucumber polysaccharide, the analysis methods of sea cucumber polysaccharide structure were comprehensively summarized, and the neutral polysaccharide, fucosylated chondroitin sulfate and sulfated fucan of sea cucumber were reviewed. The structural characteristics of sea cucumber polysaccharide were expected to provide a theoretical basis for subsequent studies on the biological activity and structure-activity relationship of sea cucumber polysaccharide.

关 键 词：海参多糖 分析方法 结构表征 

分 类 号：TS254.1[轻工技术与工程—水产品加工及贮藏工程]