Immunopathogenesis of idiopathic nephrotic syndrome  

作　　者：B.Savas F.Fofana S.Le Gouvello A.Pawlak D.Sahali M.Ollero 

机构地区：[1]UniversitéParis Est(UPEC),Facultéde Santé,UMRS 955,Créteil,F-94010,France [2]AP-HP,Groupe Henri-Mondor Albert-Chenevier,Service de Néphrologie,Créteil,F-94010,France

出　　处：《Cellular & Molecular Immunology》2022年第12期1429-1431,共3页中国免疫学杂志（英文版）

摘　　要：Idiopathic nephrotic syndrome(INS)describes a group of rare glomerular diseases characterized by massive proteinuria and hypoalbuminemia in the absence of glomerular inflammatory lesions or immunoglobulin deposits.INS includes two main entities based on kidney biopsy findings:minimal-change nephrotic syndrome(MCNS)and focal segmental glomerulosclerosis(FSGS).The treatment of INS relies on steroids and/or immunosuppressive drugs(calcineurin inhibitors,cyclophosphamide,mycophenolate mofetil,and rituximab).

关 键 词：nephrotic DRUGS PATHOGENESIS 

分 类 号：R692[医药卫生—泌尿科学]