脑血管畸形相关癫痫研究进展  

Research progress in cerebral vascular malformations-related epilepsy

作　　者：赵绍智 铁艳梅 Zhao Shaozhi;Tie Yanmei(Department of Neurosurgery,Beijing Tiantan Hospital,Capital Medical University,National Center for Clinical Medical Research of Neurological Diseases,Beijing 100070,China;Department of Neurosurgery,Brigham and Women's Hospital,Harvard Medical School,Boston 02115,USA)

机构地区：[1]首都医科大学附属北京天坛医院神经外科国家神经系统疾病临床医学研究中心,100070 [2]哈佛医学院附属布莱根妇女医院神经外科,波士顿02115

出　　处：《神经疾病与精神卫生》2023年第2期104-110,共7页Journal of Neuroscience and Mental Health

摘　　要：脑血管畸形(CVM)是指脑局部血管数量和结构的非肿瘤性发育异常所导致的疾病。癫痫发作是CVM常见的临床表现,主要存在于脑动静脉畸形和脑海绵状血管瘤两种CVM病理类型中。CVM相关癫痫为患者带来一系列的负担,是CVM临床诊疗中改善患者预后需要考虑的重要因素。现总结CVM相关癫痫的研究进展,对其发生率、发病机制、所导致的脑网络功能连接损伤、相关危险因素、个体化评估、治疗及预后等进行综述,旨在对CVM相关癫痫建立更加全面的认识,从而辅助CVM临床诊疗。Cerebral vascular malformations(CVM)are non-neoplastic lesions caused by abnormalities in the number and structure of brain vessels.Epileptic seizure is a frequent presenting symptom in patients with CVM,particularly in patients with brain arteriovenous malformations and cavernous malformations.CVMrelated epilepsy brings a series of burdens to patients,which is an essential factor to be considered in achieving a favorable prognosis for CVM.In this paper,we review the research advances in CVM-related epilepsy,including its incidence,pathogenesis,altered brain functional connectivity,risk factors,individualized evaluation,treatment,and prognosis,with the goal of assisting the diagnosis and treatment of CVM.

关 键 词：脑血管畸形 癫痫 脑动静脉畸形 脑海绵状血管瘤 神经影像 综述 

分 类 号：R742.1[医药卫生—神经病学与精神病学]