微生物脂肪酶催化合成中长链脂肪酸结构脂的研究进展  

Research progress in biosynthesis of medium-and long-chain triacylglycerol by microbial lipase

作　　者：戚彩琴 杨波[1] 杨光[1] 周盛敏 刘晓君 QI Caiqin;YANG Bo;YANG Guang;ZHOU Shengmin;LIU Xiaojun(School of Health Science and Engineering,University of Shanghai for Science and Technology,Shanghai 200093,China;Wilmar(Shanghai)Biotechnology Research&Development Center Co.Ltd.,Shanghai 200137,China)

机构地区：[1]上海理工大学健康科学与工程学院,上海200093 [2]丰益(上海)生物技术研发中心有限公司,上海200137

出　　处：《食品与发酵工业》2023年第8期310-317,共8页Food and Fermentation Industries

基　　金：上海市科技创新行动计划项目(19391904000);上海市人才发展资金资助(2018126);上海市青年科技启明星计划资助(19QB1400200)。

摘　　要：中长链脂肪酸结构脂(medium-and long-chain triacylglycerol,MLCT)是一种根据脂质在体内消化和吸收特点所设计的一种特殊结构脂质,由天然油脂改性而来,甘油分子上同时结合着中链与长链脂肪酸,因其具有独特的代谢方式与特殊的生理功能,在食品与医药方面展现出丰富的应用潜力。针对酶促合成MLCT的生物催化剂(固定化微生物脂肪酶)、合成方法、MLCT的生理功能及应用等研究现状进行综述,并对比了各种方法的优缺点及适用方向,对MLCT的研发前景进行了展望,以期为进一步研究MLCT及其他相关功能性结构脂的开发应用提供理论指导。Medium-and long-chain triacylglycerol(MLCT)is a special structural lipid designed according to the characteristics of the digestion and absorption of lipids in the body.It is modified from natural lipids and glycerol molecule combines long-chain and medium-chain fatty acids at the same time.Due to its unique metabolic mode and special physiological functions,it shows great application potential in food and medicine.In view of the research status of biological catalysts(immobilized microbial lipase),synthesis methods for enzymatic synthesis of MLCT,physiological functions,and applications of MLCT,this paper reviewed and compared the advantages and disadvantages of various methods and applicable directions,and prospected the research and development prospects of MLCT,providing theoretical guidance for the development and application of MLCT and other related functional structural lipids.

关 键 词：中长链脂肪酸结构脂 微生物脂肪酶 酶促合成 生理功能 应用 

分 类 号：TS221[轻工技术与工程—粮食、油脂及植物蛋白工程] TQ426.97[轻工技术与工程—食品科学与工程]