Focus on LPA signaling:a promising therapeutic target to foster regeneration in immune-mediated neuropathies  

作　　者：Fabian Szepanowski Mark Stettner 

机构地区：[1]Department of Neurology and Center for Translational and Behavioral Neurosciences(C-TNBS),University Medicine Essen,University Duisburg Essen,Essen,Germany

出　　处：《Neural Regeneration Research》2023年第12期2651-2652,共2页中国神经再生研究（英文版）

摘　　要：Lysophospholipids are metabolites of glycerophospholipids and sphingolipids that are commonly found as lipid constituents of cell membranes.In addition to their function as structural membrane components,certain members of the lysophospholipid family have considera ble cell signaling pro perties.Sphingosine-1-phosphate(S1P) and lysophosphatidic acid(LPA)represent the two major bioactive members of the lysophospholipid family that address specific G-protein cou pled receptors.

关 键 词：LIPIDS THERAPEUTIC FOCUS 

分 类 号：R741.05[医药卫生—神经病学与精神病学]