Impaired lysosomes in the retinal pigment epithelium play a central role in the degeneration of the neuroretina  

作　　者：Rebecca D.Miller J.Arjuna Ratnayaka 

机构地区：[1]Clinical and Experimental Sciences,Faculty of Medicine,University of Southampton,Southampton,UK

出　　处：《Neural Regeneration Research》2023年第12期2697-2698,共2页中国神经再生研究（英文版）

基　　金：Ph D Studentships from the Macular Society,Biotechnology and Biological Sciences Research Council (BBSRC) So Co Bio-DTP;funding from the Gi?t of Sight Appeal。

摘　　要：Lysosomes are highly dynamic, single membranebound compartments that are critical for maintaining cellular homeostasis. These organelles, which appear to vary between 200 nm–1 μm in diameter, originate from the maturation of endocytic vesicles and via the enrichment of newly synthesized lysosomal proteins in the trans-Golgi network.

关 键 词：CRITICAL dynamic DEGENERATION 

分 类 号：R774.1[医药卫生—眼科]