Etiology matters:genetic and acquired prion diseases engage different mechanisms at a presymptomatic stage  

作　　者：Walker S.Jackson 

机构地区：[1]Department of Biomedical and Clinical Sciences,Wallenberg Center for Molecular Medicine,Linköping University,Linköping,Sweden

出　　处：《Neural Regeneration Research》2023年第12期2707-2708,共2页中国神经再生研究（英文版）

基　　金：Wallenberg Center for Molecular Medicine,the Knut and Alice Wallenberg foundation;the King Gustaf and Queen Victoria foundation (to WSJ)。

摘　　要：One of the most enigmatic problems in biomedical research surrounds the phenomenon that neurodegenerative diseases target specific cell types and brain regions.This is difficult to explain because the proteins that cause them are widely expressed,often highest in resistant regions.This mystery is further complicated by the fact that some disease-causing proteins are associated with multiple diseases.

关 键 词：diseases DEGENERATIVE mechanisms 

分 类 号：R741[医药卫生—神经病学与精神病学]