成骨不全合并双眼角膜扩张行保留角膜缘的板层角膜移植术1例  

Limbal stem cell-sparing lamellar keratoplasty for advanced keratoglobus in a patient with osteogenesis imperfecta:a case report

作　　者：李开秀 王群[1] 李晓琴 王丽强[1] Li Kaixiu;Wang Qun;Li Xiaoqin;Wang Liqiang(The Ophthalmology Division of Chinese PLA General Hospital,Beijing 100853,China)

机构地区：[1]解放军总医院眼科医学部,北京100853

出　　处：《中华眼科杂志》2023年第4期302-304,共3页Chinese Journal of Ophthalmology

摘　　要：患者男性,15岁,生后基因检测确诊为成骨不全,视力不佳。该患者双眼全角膜不均匀薄变,呈球形扩张,右眼更重。行右眼保留角膜缘的板层角膜移植术,术后右眼视力提升,矫正视力为0.5,角膜曲率下降,角膜厚度显著增加,手术效果满意;左眼病情进展将进一步手术治疗。This 15-year-old male patient has been diagnosed with osteogenesis imperfecta through genetic testing after birth and has poor vision.His full corneas in both eyes are unevenly thinned and bulging in a spherical shape,with the right eye being more severe.He underwent a limbal stem cell-sparing lamellar keratoplasty in the right eye,resulting in improved vision with a corrected visual acuity of 0.5,a decrease in corneal curvature,and a significant increase in corneal thickness.The surgery had a satisfactory outcome.The condition of the left eye is progressing and will require further surgical treatment.

关 键 词：成骨不全 角膜疾病 

分 类 号：R779.65[医药卫生—眼科]