Initial medication adherence in newly diagnosed glaucoma patients:three adherence measures  

作　　者：Joana Menino Pedro Camacho AndréCoelho 

机构地区：[1]Escola Superior de Tecnologia da Saúde,Instituto Politécnico de Lisboa,Lisbon 1990-096,Portugal [2]H&TRC-Health&Technology Research Center,ESTeSLEscola Superior de Tecnologia da Saúde,Instituto Politécnico de Lisboa,Lisbon 1990-096,Portugal [3]iNOVA4Health,NOVA Medical School,Faculdade de Ciências Médicas,NMS,FCM,Universidade NOVA de Lisboa,Lisbon 1150-82,Portugal [4]Instituto de Oftalmologia Dr.Gama Pinto,Lisbon 1150-255,Portugal

出　　处：《International Journal of Ophthalmology(English edition)》2023年第4期630-637,共8页国际眼科杂志（英文版）

摘　　要：AIM:To determine initial medication adherence in newly diagnosed glaucoma patients treated with anti-glaucoma drugs.METHODS:This retrospective and observational study included all patients diagnosed with glaucoma in the Primary Health Care units in Portugal during the years 2012 and 2013,which in consequence received a first prescription for anti-glaucoma drugs.Data was collected from electronic prescribing records of the primary care units and from pharmacy claims records.Initiation of glaucoma treatment and early discontinuation were measured,and the combination of(non)-initiation and early discontinuation accounted for initial medication(non)-adherence.RESULTS:A total of 3548 new glaucoma patients(40.1%male;59.9%female)were included.The 1133(31.9%)patients were initially classified as non-users,since there was no pharmacy claim found for their first prescription for glaucoma treatment.Additionally,277(11.5%)patients early discontinued their treatment,acquiring only their first prescription.Overall,the initial medication non-adherence rate was 39.7%since 1410 patients either didn’t initiate treatment or discontinued it early.CONCLUSION:This study,reveals a major opportunity to improve glaucoma treatment and its control,since a large proportion of patients fail to engage with their prescribed therapy,which implies that implementation of individual or group strategies that enable patients with glaucoma to correctly perform their treatment is still needed.

关 键 词：GLAUCOMA glaucoma treatment INITIATION early discontinuation initial medication adherence 

分 类 号：R775[医药卫生—眼科]