Multiple inducible thermogenic mechanisms in the development of cold acclimatization  

作　　者：Huanyu Lu Wenjing Luo 

机构地区：[1]Department of Occupational and Environmental Health,the Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment,Shaanxi Key Laboratory,School of Public Health,Fourth Military Medical University,Xi'an 710000,China

出　　处：《Frigid Zone Medicine》2023年第2期83-91,共9页寒地医学（英文）

基　　金：the National Natural Science Foundation of China(NO.82001989,NO.82030055).

摘　　要：Extreme cold environment can threaten human health and life through increasing the risk of myocardial infarction,stroke,frostbite,and hypothermia.Insufficient heat production to maintain core body temperature is a major cause of cold injury.To cope with cold stress,human and other mammals have developed the capacity of cold acclimatization to adapt to such a harsh environment.Adaptive non-shivering thermogenesis is a ubiquitous form of cold acclimatization.This review article systematically summarizes the role of three inducible thermogenic forms,including food intake,circadian rhythms,and cold exposure in mediating non-shivering thermogenesis under cold exposure and presents the potential interventions for minimizing the adverse health consequences of cold temperature.

关 键 词：cold exposure proteomic profile HYPOTHALAMUS PITUITARY 

分 类 号：R13[医药卫生—劳动卫生]