supported by the National Natural Science Foundation of China,Nos.82304990(to NY),81973748(to JC),82174278(to JC);the National Key R&D Program of China,No.2023YFE0209500(to JC);China Postdoctoral Science Foundation,No.2023M732380(to NY);Guangzhou Key Laboratory of Formula-Pattern of Traditional Chinese Medicine,No.202102010014(to JC);Huang Zhendong Research Fund for Traditional Chinese Medicine of Jinan University,No.201911(to JC);National Innovation and Entrepreneurship Training Program for Undergraduates in China,No.202310559128(to NY and QM);Innovation and Entrepreneurship Training Program for Undergraduates at Jinan University,Nos.CX24380,CX24381(both to NY and QM)。
Early life stress correlates with a higher prevalence of neurological disorders,including autism,attention-deficit/hyperactivity disorder,schizophrenia,depression,and Parkinson's disease.These conditions,primarily inv...
BACKGROUND Pituitary macroadenomas represent a significant challenge in clinical management due to their variable presentations and complex treatment considerations.This manuscript explores the multidisciplinary appro...
This study highlights the significance of considering pituitary neuroendocrine tumor volume when determining the appropriate line of therapy for patients with acromegaly.The findings suggest that,although tumor volume...
BACKGROUND Acromegaly is caused by a pituitary neuroendocrine tumor(PitNET)with excessive production of growth hormone(GH),leading to multisystem complications.Previous studies have identified predictors of disease pe...
Growth hormone deficiency(GHD)is the most common pituitary hormone deficiency and is clinically characterized by short stature,delayed bone age and central distribution of body fat,and it has also been proven to be mi...
Introduction: Pituitary neuroendocrine tumor (PitNET) may present multisecreting forms. Identifying its forms helps to guide management. This management is a real challenge, given the limited resources in our regions....
the Science and Technology Program of Nantong Health Committee,No.MA2019003,and No.MA2021017;Science and Technology Program of Nantong City,No.Key003,and No.JCZ2022040;Kangda College of Nanjing Medical University,No.KD2021JYYJYB025,No.KD2022KYJJZD019,and No.KD2022KYJJZD022.
Pituitary tumor is a common neuroendocrine tumor,but there are also rare clinical metastases at this site,which are generally transferred from extrabellar tumors.Although the clinical incidence is low,the prognosis is...
supported by the National Natural Science Foundation of China (No. 81973639 and 81573712);the Innovative Research Team of High-level Local Universities in Shanghai;Shanghai Key Laboratory for Acupuncture Mechanism and Acupoint Function (No. 21DZ2271800)。
The hypothalamic–pituitary–adrenal(HPA) axis is a critical component of the neuroendocrine system,playing a central role in regulating the body's stress response and modulating various physiological processes. Dysre...
supported by UK-Japan Research Collaboration Grants from the Ministry of the Environment,Japan,and JSPS KAKENHI grant No.18H02281 awarded to T.K.
Gonadal soma-derived factor(Gsdf)is a member of the transforming growth factor beta(TGF-β)superfamily and a teleost-specific gene.Early studies suggested that Gsdf promotes spermatogonial proliferation;however recent...
Major depressive disorder(MDD)and type 2 diabetes(T2D)are two common complex multifactorial disorders that share several genetic and environmental risk factors such as hypercortisolism and related genes'riskvariants w...