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supported by the National Natural Science Foundation of China(Nos.32273127,31771648,and 31672653);the Scientific Research Foundation of Jimei University(No.ZQ2020003),China。
The clustered regularly interspaced short palindromic repeats(CRISPR)/CRISPR-associated protein 9(Cas9)system,belonging to the typeⅡCRISPR/Cas system,is an effective gene-editing tool widely used in different organis...
The National Natural Science Foundation of China under contract No.42106119;the Department of Science and Technology of Fujian Province under contract Nos 2022J02052,2020J05175 and 2020J05178;the Fujian Provincial Department of Ocean and Fisheries under contract No.FJHJF-L-2022-12;the Yancheng Fishery High Quality Development Project under contract No.YCSCYJ2021023.
In the coastal environment,the co-occurrence of antibiotic and nanoplastic pollution is common.Investigating their individual and combined toxicity to marine organisms is of great necessity.In the present study,the re...
supported by UK-Japan Research Collaboration Grants from the Ministry of the Environment,Japan,and JSPS KAKENHI grant No.18H02281 awarded to T.K.
Gonadal soma-derived factor(Gsdf)is a member of the transforming growth factor beta(TGF-β)superfamily and a teleost-specific gene.Early studies suggested that Gsdf promotes spermatogonial proliferation;however recent...
supported in part by a Grant-in-Aid for Scientific Research from JSPS(15K07127 to AK and MK).
A basic helix-loop-helix transcription factor,figα,is one of the earliest marker genes of oocyte differentiation in vertebrates.In the present study,we made figαknockout medaka by CRISPR/Cas9,expecting aborted progr...
supported by the National Natural Science Foundation of China (Nos.22006159 and 31971236);the Research Grants Council Theme-Based Research Scheme (No.T21-602/16-R);the Natural Science Foundation of Hubei Province,China (No.2021CFA086);the State Key Laboratory of Freshwater Ecology and Biotechnology (No.2022FBZ02)。
Perfluorobutanesulfonate(PFBS)is an emerging pollutant capable of potently disrupting the sex and thyroid endocrine systems of teleosts.However,the hypoxic and temporal variation in PFBS endocrine disrupting toxicity ...
supported by the Southern Marine Science and Engineering Guangdong Laboratory(Guangzhou)(No.SMSEGL20SC02);the National Natural Science Foundation of China(No.41977371);a Project grant from the Shenzhen and Technology Innovation Commission(No.JCYJ20170818094137791);supported by the National Institute of Environmental Health Sciences of the National Institutes of Health under award number 1R15ES032936-01.
Benzo[a]pyrene(BaP),a ubiquitous pollutant,raises environmental health concerns due to induction of bone toxicity in the unexposed offspring.Exposure of F0 ancestor medaka(Oryzias latipes)to 1μg/L BaP for 21 days cau...
This work was supported by the National Natural Science Foundation of China(31672700);National Key R&D Program of China(2018YFD0901205).
The gonad specific expression of insulin-like growth factor 3(igf3)has suggested an important role of igf3 in fish reproduction.In this study,medaka igf3 was isolated and its expression patterns were compared with igf...
the National Key R&D Program of China(2018YFD0901205);National Natural Science Foundation of China(31672700).
Numerous studies have showed that sox3 is involved in neurogenesis and sex differentiation in vertebrates.However,the accurate expression pattern is still unclear in fish.In this study,medaka sox3 was isolated and its...
This study was supported by the National Natural Science Foundation of China(Nos.31771648 and 31672653);the Scientific Research Foundation of Jimei University(No.ZQ2020003);the National Key Basic Research Program of China(No.2013CB967700).
Generation of mutants with clustered regularly interspaced short palindromic repeats(CRISPR)/CRISPR-associated protein 9(Cas9)is commonly carried out in fish species by co-injecting a mixture of Cas9 messenger RNA(mRN...
This work was supported by the National Natural Science Foundation of China(31672700);National Key R&D Program of China(2018YFD0901205).
Germ cells of many organisms exhibit a unique perinuclear cytoplasmic cloud-like structure called the chromatoid body(CB).Specific components of the CB,such as vasa,are crucial for germline development.Herein we ident...