基于三维人脸模板的外鼻缺损三维形态补全方法初探  

Preliminary study on three-dimensional morphological reconstruction method for external nose defect based on three-dimensional face template

作　　者：温奥楠 王勇 叶红强[3] 高梓翔 朱玉佳 秦庆钊 胡慧珍 刘云松[3] 赵一姣[1] Wen Aonan;Wang Yong;Ye Hongqiang;Gao Zixiang;Zhu Yujia;Qin Qingzhao;Hu Huizhen;Liu Yunsong;Zhao Yijiao(Center of Digital Dentistry,Faculty of Prosthodontics,Peking University School and Hospital of Stomatology&National Center for Stomatology&National Clinical Research Center for Oral Diseases&National Engineering Research Center of Oral Biomaterials and Digital Medical Devices&Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health&Beijing Key Laboratory of Digital Stomatology,Beijing 100081,China;Institute of Medical Technology,Peking University Health Science Center,Beijing 100191,China;Department of Prosthodontics,Peking University School and Hospital of Stomatology&National Center for Stomatology&National Clinical Research Center for Oral Diseases&National Engineering Research Center of Oral Biomaterials and Digital Medical Devices&Beijing Key Laboratory of Digital Stomatology,Beijing 100081,China;Special Dental Department,Hospital of Stomatology Lanzhou University,Lanzhou 730031,China)

机构地区：[1]北京大学口腔医学院·口腔医院口腔医学数字化研究中心、口腔修复教研室、国家口腔医学中心、国家口腔疾病临床医学研究中心、口腔生物材料和数字诊疗装备国家工程研究中心、国家卫生健康委口腔医学计算机应用工程技术研究中心、口腔数字医学北京市重点实验室,北京100081 [2]北京大学医学部医学技术研究院,北京100191 [3]北京大学口腔医学院·口腔医院修复科、国家口腔医学中心、国家口腔疾病临床医学研究中心、口腔生物材料和数字诊疗装备国家工程研究中心、口腔数字医学北京市重点实验室,北京100081 [4]兰州市口腔医院特诊科,兰州730031

出　　处：《中华口腔医学杂志》2023年第5期414-421,共8页Chinese Journal of Stomatology

基　　金：国家自然科学基金(82071171,82271039);甘肃省重点研发计划(21YF5FA165);北大医学顶尖学科及学科群发展专项(BMU2022XKQ003)。

摘　　要：目的基于三维人脸模板的非刚性配准过程探讨外鼻缺损三维形态补全方法,为鼻赝复体的数字化设计提供新的解决方案。方法选取2022年6至12月于北京大学口腔医学院·口腔医院修复科就诊的牙体缺损或缺失男性患者20例,年龄18~45岁,采集患者原始三维颜面数据,用Geomagic Wrap 2021软件构建外鼻缺损三维颜面数据。使用课题组前期研究中构建的结构化三维人脸模板数据,基于非缺损区形态,通过MeshMonk程序(一种非刚性配准算法)将三维人脸模板变形配准至外鼻缺损三维颜面数据上,获得三维人脸模板个性化变形后的数据,即补全人脸三维数据。基于外鼻缺损三维颜面数据的缺损边界,在补全人脸三维数据上裁剪出补全外鼻三维数据。对比分析补全人脸三维数据与原始三维颜面数据的鼻面角和鼻唇角,测量补全人脸三维数据鼻长与中面高、鼻宽与内眦间距的比值,评价补全外鼻三维数据的边缘曲线与外鼻缺损三维颜面数据缺损边缘曲线的边缘密合度,并分析补全外鼻三维数据与原始三维颜面数据鼻部相同标志点间距离值。结果20例原始三维颜面数据与补全人脸三维数据的鼻面角(分别为28.2°±2.9°、28.4°±3.5°)、鼻唇角[分别为95.4°(19.2°)、99.9°(9.5°)]差异均无统计学意义(t=-0.23,P=0.823;Z=-1.72,P=0.086)。补全人脸三维数据鼻长与中面高的比值为0.63±0.03,鼻宽与内眦间距的比值为1.07±0.08。补全外鼻三维数据的边缘曲线与外鼻缺损三维颜面数据缺损边缘曲线的曲线偏差(均方根值)为(0.37±0.09)mm、最大偏差为(1.14±0.32)mm,曲线偏差值位于±1 mm之内的占比为(97±3)%。补全人脸三维数据与原始三维颜面数据上对应鼻部标志点间距离分别为鼻根点[1.52(1.92)]mm,鼻尖点(3.27±1.21)mm,鼻下点(1.99±1.09)mm,右鼻翼点(2.64±1.34)mm,左鼻翼点(2.42±1.38)mm。结论本项研究提出的外鼻缺损三维形态补全�Objective To provide a new solution for the digital design of nasal prostheses,this study explores the three-dimensional(3D)facial morphology completion method for external nasal defects based on the non-rigid registration process of 3D face template.Methods A total of 20 male patients with tooth defect and dentition defect who visited the Department of Prosthodontics,Peking University School and Hospital of Stomatology from June to December 2022 were selected,age 18-45 years old.The original 3D facial data of patients were collected,and the 3D facial data of the external nose defect was constructed in Geomagic Wrap 2021 software.Using the structured 3D face template data constructed in the previous research of the research group,the 3D face template was deformed and registered to the 3D facial data of external nose defect(based on the morphology of non-defective area)by non-rigid registration algorithm(MeshMonk program),and the personalized deformed data of the 3D face template was obtained,as the complemented facial 3D data.Based on the defect boundary of the 3D facial data of the external nose defect,the complemented external nose 3D data can be cut out from the complemented facial 3D data.Then the nasofacial angle and nasolabial angle of the complemented facial 3D data and the original 3D facial data was compared and analyzed,the ratio between the nose length and mid-face height,nose width and medial canthal distance of the complemented facial 3D data was measured,the edge fit between the edge curve of the complemented external nose 3D data and the defect edge curve of the 3D facial data of external nose defect was evaluated,and the morphological difference of the nose between the complemented external nose 3D data and the original 3D facial data was analyzed.Results There was no significant statistically difference(t=-0.23,P=0.823;Z=-1.72,P=0.086)in the nasofacial angle(28.2°±2.9°,28.4°±3.5°respectively)and nasolabial angle[95.4°(19.2°),99.9°(9.5°)respectively]between the 20 original 3D facial data

关 键 词：鼻 颌面假体 假体设计 计算机辅助设计 三维人脸模板 非刚性配准 

分 类 号：R782.2[医药卫生—口腔医学]