颅颌面肿瘤切除后骨缺损虚拟重建的研究进展  

Research progress of virtual reconstruction of craniomaxillofacial bone defects

作　　者：熊宇韬 张雨楠 曾维[1] 刘灿[2] 汤炜[1] XIONG Yu-tao;ZHANG Yu-nan;ZENG Wei;LIU Can;TANG Wei(Department of Oral and Macillofacial Surgery,State Key Laboratory of Oral Diseases,Natiomal Clinical Research Centre for Oral Diseases,West China Hospital of Stomatology,Sichuan University,Chengdu 610041,China;Scientific Research De partment,Beijing Jimafei Technology Derelopment Co.,LTD,Beijing 102300,China)

机构地区：[1]四川大学华西口腔医院口腔颌面外科·口腔疾病国家重点实验室·国家口腔疾病临床研究中心,四川成都610041 [2]北京吉马飞科技发展有限公司科研部,北京102300

出　　处：《中华肿瘤防治杂志》2023年第2期67-72,共6页Chinese Journal of Cancer Prevention and Treatment

基　　金：四川省区域创新合作项目(2020YFG0012);科技助力经济2020重点专项(SQ2020YFF0411258);。

摘　　要：颅颌面肿瘤在切除后会造成骨质结构的缺失或错乱,严重影响了患者的生理功能和心理健康,因此后续重建手术尤为重要。而颅颌面骨复杂的解剖结构以及狭小的视野使得重建过程变得复杂和困难。虚拟手术计划为颅颌面骨重建提供了客观的设计过程与先验手术的机会,而如何获得一个正确的术前虚拟参考模型是术前计划的关键。目前的虚拟重建包括镜像、插值法、可变形模板和逐层重建等方法,其本质都是在剩余骨质信息的基础上,利用数学模型或参考正常人生理结构来获取额外信息完成缺损重建。深度学习将虚拟重建问题理解为形状的补全任务,实现了重建过程的(半)自动化。本研究回顾现有颅颌面肿瘤切除后骨缺损虚拟重建方案,按照方法学提供了全新的分类并对各方案进行评价。Craniomaxillofacial tumors can cause the loss or disorder of bone structure after resection,which seriously affects the patient's physiological function and mental health,so the follow-up reconstruction surgery is particularly important.However,the complex anatomy and narrow visual field of craniomaxillofacial bone make the reconstruction process complicated and difficult.Virtual surgical planning provides an objective design process and a prior surgical opportunity for craniomaxillofacial bone reconstruction;however,obtaining a correct preoperative virtual reference model is the key to preoperative planning.Current virtual reconstruction methods include mirroring,interpolation,deformable template,layer-bylayer reconstruction,etc.The essence of virtual reconstruction is to obtain additional information based on residual bone information and complete the reconstruction of defects by using mathematical models or referring to typical human physiological structures.Deep learning understands the virtual reconstruction problem as a shape completion task and realizes the(semi-)automation of the reconstruction process.This paper reviewed the existing virtual plans for virtual reconstruction of bone defects after craniomaxillofacial tumor resection,provided a new classification according to the methodology and evaluates eachmethod.

关 键 词：颅颌面 肿瘤 骨缺损 修复重建 计算机辅助外科 

分 类 号：R739.91[医药卫生—肿瘤]