Substrate stiffness in nerve cells  

作　　者：Weijin Si Jihong Gong Xiaofei Yang 

机构地区：[1]Key Laboratory of Cognitive Science,Hubei Key Laboratory of Medical Information Analysis and Tumor Diagnosis&Treatment,Laboratory of Membrane Ion Channels and Medicine,College of Biomedical Engineering,South-Central Minzu University,Wuhan 430074,China

出　　处：《Brain Science Advances》2023年第1期24-34,共11页神经科学（英文）

基　　金：supported by the National Natural Science Foundation of China(Grant Nos.32170699 and 32200560);National Science Foundation of Hubei(Grant Nos.2020CFA025 and 2022CFB906);the Fundamental Research Funds for the Central Universities of South-Central Minzu University(Grant No.CZQ22005).

摘　　要：Recently, substrate stiffness has been involved in the physiology and pathology of the nervous system. However, the role and function of substrate stiffness remain unclear. Here, we review known effects of substrate stiffness on nerve cell morphology and function in the central and peripheral nervous systems and their involvement in pathology. We hope this review will clarify the research status of substrate stiffness in nerve cells and neurological disorder.

关 键 词：substrate stiffness nerve cell NEURITE SYNAPSE PATHOLOGY neurological diseases 

分 类 号：R338[医药卫生—人体生理学]