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NEURITE: 作品数：39被引量：97H指数：5; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：官孝群王毅超刘银坤宋后燕陈中伟更多>>; 相关机构：复旦大学上海中医药大学更多>>; 相关期刊：《Science China(Life Sciences)》《Science China Chemistry》《World Journal of Gastroenterology》《Pharmacology & Pharmacy》更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划上海市自然科学基金国家科技部专项基金更多>>

Empowering the NSC-34 cell line as a motor neuron model: Cytosine arabinoside's action: 《Neural Regeneration Research》2026年第1期357-364,共8页Giuseppe Vitale Susanna Amadio Francesco Liguori Cinzia Volonté; supported by FATALSDrug Project [Progetti di Ricerca@CNR SAC.AD002.173.058] from National Research Council,Italy (to CV)。; The NSC-34 cell line is a widely recognized motor neuron model and various neuronal differentiation protocols have been exploited. Under previously reported experimental conditions, only part of the cells resemble dif...; 关键词：cytosine arabinoside Islet2 Hb9 Ki67 mitosis inhibition neurite initiation neurite regeneration neuronal differentiation protocol NSC-34 P75

Modulation of the Nogo signaling pathway to overcome amyloid-β-mediated neurite inhibition in human pluripotent stem cell-derived neurites: 《Neural Regeneration Research》2025年第9期2645-2654,共10页Kirsty Goncalves Stefan Przyborski; supported by a BBSRC CASE training studentship,No.BB/K011413/1(to KG)。; Neuronal cell death and the loss of connectivity are two of the primary pathological mechanisms underlying Alzheimer's disease.The accumulation of amyloid-βpeptides,a key hallmark of Alzheimer's disease,is believed t...; 关键词：Alzheimer's disease induced pluripotent stem cell neurite outgrowth neuron NOGO Rho A ROCK stem cell three-dimensional culture

Neuronal guidance factor Sema3A inhibits neurite ingrowth and prevents chondrocyte hypertrophy in the degeneration of knee cartilage in mice,monkeys and humans: 《Bone Research》2025年第1期75-90,共16页Shishu Huang Dashuang Gao Zhenxia Li Hongchen He Xi Yu Xuanhe You Diwei Wu Ze Du Jiancheng Zeng Xiaojun Shi Qinshen Hu Yong Nie Zhong Zhang Zeyu Luo Duan Wang Zhihe Zhao Lingli Li Guanglin Wang Liping Wang Zongke Zhou Di Chen Fan Yang; partly National Key R&D Program of China(2023YFA1801200,2023YFA1801202);Major Program of the National Natural Science Foundation of China(T2394532);National Natural Science Foundation of China(82072489);The Foundation of Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions(NYKFKT2019007);Shenzhen Medical Research Fund(B2302011);The Sanming Project of Medicine in Shenzhen(SZZYSM202311013);The China Postdoctoral Science Foundational,2023M743679;Shenzhen Science and Technology Research Funding(JCYJ20220818101414032);Key Research Project of Science&Technology Department of Sichuan Province,China(2024YFFK0041)。; Osteoarthritis(OA)is a degenerative joint disease accompanied with the loss of cartilage and consequent nociceptive symptoms.Normal articular cartilage maintains at aneural state.Neuron guidance factor Semaphorin 3A(S...; 关键词：SEMA3A CARTILAGE HYPERTROPHY

Activation of cerebral Ras-related C3 botulinum toxin substrate(Rac) 1 promotes post-ischemic stroke functional recovery in aged mice被引量：2: 《Neural Regeneration Research》2024年第4期881-886,共6页Fan Bu Jia-Wei Min Md Abdur Razzaque Ahmad El Hamamy Anthony Patrizz Li Qi Akihiko Urayama Jun Li; supported by NIH grants RF1 AG069466(to JL and LDM),R01 NS099628(to JL),and AG069466(to JL and LDM);the American Heart Association award 20POST35180172(to FB)。; Brain functional impairment after stroke is common;however,the molecular mechanisms of post-stroke recovery remain unclear.It is well-recognized that age is the most important independent predictor of poor outcomes af...; 关键词：aging angiogenesis brain-derived neurotrophic factor(BDNF) cerebral ischemia cognitive recovery NEURITE PAK1 RAC1 sensorimotor recovery

Role of transforming growth factor-βin peripheral nerve regeneration被引量：5: 《Neural Regeneration Research》2024年第2期380-386,共7页Zihan Ding Maorong Jiang Jiaxi Qian Dandan Gu Huiyuan Bai Min Cai Dengbing Yao; supported by the National Natural Science Foundation of China,Nos.31971277 and 31950410551(both to DY)。; Injuries caused by trauma and neurodegenerative diseases can damage the peripheral nervous system and cause functional deficits.Unlike in the central nervous system,damaged axons in peripheral nerves can be induced to...; 关键词：MYELINATION nerve repair and regeneration NEURITE NEUROINFLAMMATION peripheral nerve injury Schwann cell transforming growth factor-β Wallerian degeneration

Molecular mechanisms of neurite regeneration and repair:insights from C.elegans and Drosophila: 《Cell Regeneration》2023年第1期284-294,共11页Xiaofan Liu Yuqing Zhao Wei Zou; supported by grants from the National Science Foundation of China(31970919)to W.Z.; The difficulties of injured and degenerated neurons to regenerate neurites and regain functions are more significant than in other body tissues,making neurodegenerative and related diseases hard to cure.Uncovering the...; 关键词：Neurite regeneration Neurite repair Caenorhabditis elegans Drosophila melanogaster Genetic manipulation Live imaging Subcellular structures AXOTOMY Dendrotomy DLK-1

Tissue Microstructure Estimation of SANDI Based on Deep Network: 《Journal of Beijing Institute of Technology》2023年第5期600-608,共9页Bingnan Gao Zhiwen Liu; Diffusion magnetic resonance imaging(dMRI)is a noninvasive method to capture the anisotropic pattern of water displacement in the neuronal tissue.The soma and neurite density imaging(SANDI)model introduced soma size a...; 关键词：diffusion magnetic resonance imaging(dMRI) tissue microstructure soma and neurite density imaging(SANDI) deep learning

Novel insights into the mechanism of reactive oxygen species-mediated neurodegeneration被引量：2: 《Neural Regeneration Research》2023年第4期746-749,共4页Shuji Wakatsuki Toshiyuki Araki; Neurite degeneration,a major component of many neurodegenerative diseases,such as Parkinson’s disease,Alzheimer’s disease,and amyotrophic lateral sclerosis,is not part of the typical apoptosis signaling mechanism,bu...; 关键词：neurite degeneration oxidative stress PHOSPHORYLATION reactive oxygen species ubiquitin ligase

Substrate stiffness in nerve cells: 《Brain Science Advances》2023年第1期24-34,共11页Weijin Si Jihong Gong Xiaofei Yang; supported by the National Natural Science Foundation of China(Grant Nos.32170699 and 32200560);National Science Foundation of Hubei(Grant Nos.2020CFA025 and 2022CFB906);the Fundamental Research Funds for the Central Universities of South-Central Minzu University(Grant No.CZQ22005).; Recently, substrate stiffness has been involved in the physiology and pathology of the nervous system. However, the role and function of substrate stiffness remain unclear. Here, we review known effects of substrate s...; 关键词：substrate stiffness nerve cell NEURITE SYNAPSE PATHOLOGY neurological diseases

Preliminary examination of early neuroconnectivity features in the R6/1 mouse model of Huntington's disease by ultra-high field diffusion MRI: 《Neural Regeneration Research》2022年第5期983-986,共4页Rodolfo G.Gatto Carina Weissmann; supported in part by the High Magnetic Field Laboratory(NHMFL)and Advanced Magnetic Resonance Imaging and Spectroscopy(AMRIS)under Magnetic Laboratory Visiting Scientist Program Award,No.VSP#327(to RG)。; During the last decades,advances in the understanding of genetic,cellular,and microstructural alterations associated to Huntington's disease(HD)have improved the understanding of this progressive and fatal illness.How...; 关键词：brain repair diffusion tensor imaging Huntington's disease neurite orientation dispersion and density imaging neuroconnectivity NEUROINFLAMMATION NEUROPLASTICITY NEUROREGENERATION R6/1 mice ultra-high field diffusion MRI

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