supported by a BBSRC CASE training studentship,No.BB/K011413/1(to KG)。
Neuronal cell death and the loss of connectivity are two of the primary pathological mechanisms underlying Alzheimer's disease.The accumulation of amyloid-βpeptides,a key hallmark of Alzheimer's disease,is believed t...
supported by NIH grants RF1 AG069466(to JL and LDM),R01 NS099628(to JL),and AG069466(to JL and LDM);the American Heart Association award 20POST35180172(to FB)。
Brain functional impairment after stroke is common;however,the molecular mechanisms of post-stroke recovery remain unclear.It is well-recognized that age is the most important independent predictor of poor outcomes af...
supported by the National Natural Science Foundation of China,Nos.31971277 and 31950410551(both to DY)。
Injuries caused by trauma and neurodegenerative diseases can damage the peripheral nervous system and cause functional deficits.Unlike in the central nervous system,damaged axons in peripheral nerves can be induced to...
supported by grants from the National Science Foundation of China(31970919)to W.Z.
The difficulties of injured and degenerated neurons to regenerate neurites and regain functions are more significant than in other body tissues,making neurodegenerative and related diseases hard to cure.Uncovering the...
Diffusion magnetic resonance imaging(dMRI)is a noninvasive method to capture the anisotropic pattern of water displacement in the neuronal tissue.The soma and neurite density imaging(SANDI)model introduced soma size a...
Neurite degeneration,a major component of many neurodegenerative diseases,such as Parkinson’s disease,Alzheimer’s disease,and amyotrophic lateral sclerosis,is not part of the typical apoptosis signaling mechanism,bu...
supported by the National Natural Science Foundation of China(Grant Nos.32170699 and 32200560);National Science Foundation of Hubei(Grant Nos.2020CFA025 and 2022CFB906);the Fundamental Research Funds for the Central Universities of South-Central Minzu University(Grant No.CZQ22005).
Recently, substrate stiffness has been involved in the physiology and pathology of the nervous system. However, the role and function of substrate stiffness remain unclear. Here, we review known effects of substrate s...
supported in part by the High Magnetic Field Laboratory(NHMFL)and Advanced Magnetic Resonance Imaging and Spectroscopy(AMRIS)under Magnetic Laboratory Visiting Scientist Program Award,No.VSP#327(to RG)。
During the last decades,advances in the understanding of genetic,cellular,and microstructural alterations associated to Huntington's disease(HD)have improved the understanding of this progressive and fatal illness.How...
supported by the National Natural Science Foundation of China[No.31971163];the Shanghai“Rising Stars of Medical Talent”Youth Development Program[2020-087]。
In previous decades,people were concerned about their health because of growing environmental influences.The advancements in pulsed power technologies have increased the availability of microwave transmitters.The poss...
National Natural Science Foundation of China(No.81570462,No.81730049,and No.81801666).
The purpose of this work was to demonstrate the feasibility of neurite orientation dispersion and density imaging(NODDI)in characterizing the brain tissue microstructural changes of middle cerebral artery occlusion(MC...