食源性生物活性肽的免疫功能研究进展  

Research progress on immune function of food-derived bioactive peptides

作　　者：张芷萌 倪策 欧晓晖 曹天红 程云辉[1,2] 文李 ZHANG Zhi-meng;NI Ce;OU Xiao-hui;CAO Tian-hong;CHENG Yun-hui;WEN Li(Changsha University of Science and Technology,Changsha,Hunan 410014,China;College of Food Science and Engineering,Qilu University of Technology〔Shandong Academy of Sciences〕,Jinan,Shandong 250353,China)

机构地区：[1]长沙理工大学食品与生物工程学院,湖南长沙410014 [2]齐鲁工业大学〔山东省科学院〕食品科学与工程学院,山东济南250353

出　　处：《食品与机械》2023年第5期193-202,共10页Food and Machinery

基　　金：湖南省自然科学基金面上项目(编号:2021JJ2024);国家自然科学基金面上项目(编号:31972077)。

摘　　要：食源性生物活性肽通过调控体内信号转导通路并影响细胞因子的表达来发挥免疫调节功能。文章综述了多种食源性蛋白质水解物和生物活性肽对细胞、动物及人体的免疫调节作用,阐述了食源性免疫活性肽的作用机制,并对其应用前景进行展望。Food-derived bioactive peptides play an immunoregulation role by regulating signal pathways and influencing the expression of cytokines in vivo.This review summarizes immunoregulatory effects of the food-derived protein hydrolysates and bioactive peptides on cells,animal models and human beings,and the immune mechanism of food-derived bioactive peptides in different models is explained.Finally,the future application of bioactive peptides is prospected.

关 键 词：生物活性肽 免疫 免疫活性肽 炎症反应 细胞模型 动物模型 

分 类 号：TS201.2[轻工技术与工程—食品科学]