Gaining access to acetyl-CoA by peroxisomal surface display  

作　　者：Thomas Perrot Sebastien Besseau Nicolas Papon Vincent Courdavault 

机构地区：[1]Biomolecules et Biotechnologies Vegetales,BBV,EA2106,Universite de Tours,Tours,France [2]Univ Angers,Univ Brest,IRF,SFR ICAT,F-49000,Angers,France

出　　处：《Synthetic and Systems Biotechnology》2023年第2期224-226,共3页合成和系统生物技术（英文）

基　　金：funding from the EU Horizon 2020 research and innovation program(MIAMi project-Grant agreement N°814645);ARD-CVL Biopharmaceutical program of the Region Centre Val de Loire(ETOPOCentre project),Le Studium Institute(Consortium Fellowship)and ANR(project MIACYC-ANR-20-CE43-0010).

摘　　要：Synthetic biology is constantly making progress for producing compounds on demand.Recently,Yocum and collaborators have developed an outstanding approach based on the anchoring of biosynthetic enzymes to the peroxisomal membrane.This allowed access to an untapped resource of acetyl-CoA and stimulated the synthesis of a valuable polyketide.

关 键 词：Synthetic biology Enzymes colocalization Peroxisomal membrane ACETYL-COA POLYKETIDES 

分 类 号：Q-4[生物学]