Cetirizine-induced hepatotoxicity:case series and review of the literature  

西替利嗪引起的肝中毒:病例系列报道和文献复习

作　　者：Adil Coskun Irfan Yavasoglu M.Hadi Yasa Nil Culhaci Vahit Yukselen 

机构地区：[1]Department of Gastroenterology,Adnan Menderes University,School of Medicine,Aydin,Turkey [2]Deparment of Hematology,Adnan Menderes University,School of Medicine,Aydin,Turkey [3]Department of Pathology,Adnan Menderes University,School of Medicine,Aydin,Turkey

出　　处：《Gastroenterology Report》2018年第3期228-230,I0003,共4页胃肠病学报道（英文）

摘　　要：Drug-induced liver damage is a frequently encountered clinical table caused by many drugs.Cetirizine is a widely preferred and prescribed antihistaminic agent for allergic disorders due to its non-sedative properties.In view of the literature,we present four cases of hepatotoxicity due to cetirizine use.We conclude that in patients with high levels of liver enzymes of unknown origin,cetirizine as well as other hepatotoxic drugs should be reconsidered.Drug-induced liver damage is a frequently encountered clinical table caused by many drugs.Cetirizine is a widely preferred and prescribed antihistaminic agent for allergic disorders due to its non-sedative properties.In view of the literature,we present four cases of hepatotoxicity due to cetirizine use.We conclude that in patients with high levels of liver enzymes of unknown origin,cetirizine as well as other hepatotoxic drugs should be reconsidered.

关 键 词：CETIRIZINE HEPATOTOXICITY 

分 类 号：R57[医药卫生—消化系统]