Biologics:how far can they go in Crohn’s disease?  

作　　者：Katie A.Dunleavy Darrell S.Pardi 

机构地区：[1]Division of Gastroenterology and Hepatology,Mayo Clinic,Rochester,MN,USA

出　　处：《Gastroenterology Report》2022年第1期155-170,共16页胃肠病学报道（英文）

摘　　要：Crohn’s disease is a chronic gastrointestinal inflammatory disorder,characterized by episodes of relapsing and remitting flares.As the disease mechanism becomes better elucidated,there is a significant increase in the number of available biologic therapies.This article summarizes and synthesizes current Food and Drug Administration-approved biological therapy for Crohn’s disease and examines the positioning of medical therapy as emerging biologics break onto the market.

关 键 词：Crohn’s disease medical treatment BIOLOGICS anti-TNFs anti-integrins anti-interleukins JAK inhibitors S1Pinhibitors 

分 类 号：R574.62[医药卫生—消化系统]