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作 者:潘杰[1] Pan Jie(School of Life Sciences,Shandong Normal University,250014,Jinan,China)
出 处:《山东师范大学学报(自然科学版)》2023年第2期97-121,共25页Journal of Shandong Normal University(Natural Science)
摘 要:肥胖是体内白色脂肪组织过度积聚的状态,给肥胖者生理和心理健康均可造成负面影响.近年来我国儿童超重和肥胖率快速增加,已超过一些发达国家的水平.肥胖儿童体质偏低,更增加其成年后患肥胖相关疾病的风险,加重家庭和社会负担,严峻形势不容小觑.日常生活中过量摄入高油脂、高糖类等高热量饮食,“进大于出”,膳食结构多样性减少加之睡眠和运动量不足是导致肥胖的主要外因.纠正这些不良生活习惯是防治肥胖的根本.本文从生命科学的角度,概述肥胖对儿童健康的危害,结合肥胖发生发展分子机制的研究进展,评述从源头上防治儿童肥胖的策略,希望为从事防治肥胖及相关疾病研究和关注后代健康的家庭,提供参考资料.Obesity is a state of excessive accumulation of white adipose tissue in the body,which can cause negative effects on the physical and mental health of obese man.In recent years,the rate of overweight and obesity in Chinese children has been increasing rapidly,and has surpassed the level of some developed countries.The low constitution of obese children increases the risk of obesity-related diseases in adulthood and aggravates the burden on family and society.Excessive intake of high-calorie diets such as high fat and high sugar in daily life,decreased dietary diversity and insufficient sleep and exercise are the main external causes of obesity.Correcting these bad habits is the fundamental to prevent obesity.In this review paper,the harm of obesity to health of children is summarized from the point of view of life science,and the strategies of preventing and treating childhood obesity from the source are reviewed in the light of the research progress of molecular mechanism of the occurrence and development of obesity,it is hoped to provide reference materials for the persons who are engaged in the research on the prevention and treatment of obesity and related diseases and concerned about the health of their offspring.
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