儿童神经肌肉病的PICU综合治疗  

Complex treatment of neuromuscular diseases in PICU

作　　者：颜景礼 许巍[1] Yan Jingli;Xu Wei(Pediatric Intensive Care Unit,Shengjing Hospital of China Medical University,National Children′s Regional Medical Center(Northeast),Shenyang 110004,China)

机构地区：[1]国家儿童区域医疗中心(东北)中国医科大学附属盛京医院小儿重症监护病房,沈阳110004

出　　处：《中国小儿急救医学》2023年第6期417-421,共5页Chinese Pediatric Emergency Medicine

基　　金：辽宁省教育厅基本科研项目(LJKMZ20221186);沈阳市公共卫生研发专项(22-321-33-14)。

摘　　要：神经肌肉病是一组影响脊髓前角细胞、周围神经、神经肌肉接头和骨骼肌的疾病。一部分神经肌肉病患儿病情进展迅速,威胁呼吸和延髓功能。收入PICU的神经肌肉病患儿的主要病因包括神经功能严重受损、感染、合并症(如呼吸衰竭、心力衰竭等)、意外情况以及其他导致原发病加重的情况。在每一种情况下,及时识别、制定特定疗法和支持性护理措施都可以改善患儿预后。Neuromuscular diseases are a group of disorders that affect the anterior horn cells of the spinal cord,peripheral nerves,neuromuscular junction and skeletal muscle.A subset of children with neuromuscular disease have rapidly progressive conditions that threaten respiratory and medulla oblongata function.The main causes of neuromuscular disease in PICU include severe neurological impairment,infections,comorbidities,unexpected situations,and other conditions that can exacerbate the primary disease.In each case,timely identification and development of the specific therapies and supportive care measures could improve prognosis.

关 键 词：神经肌肉病 呼吸肌无力 镇静 危重症相关虚弱 

分 类 号：R746[医药卫生—神经病学与精神病学]