磁共振成像在肌病中的临床应用研究进展  

Progressions in clinical application of magnetic resonance imaging in myopathy

作　　者：徐婷 郭应坤[1] 许华燕 蔡晓唐[2] XU Ting;GUO Yingkun;XU Huayan;CAI Xiaotang(Department of Radiology,West China Second Hospital,Sichuan University,Key Laboratory of Obstetric&Gynecologic and Pediatric Diseases and Birth Defect of Ministry of Education,Chengdu 610041,China;Department of Pediatric Neurology,West China Second Hospital,Sichuan University,Chengdu 610041,China)

机构地区：[1]四川大学华西第二医院放射科出生缺陷与相关妇儿疾病教育部重点实验室,成都610041 [2]四川大学华西第二医院小儿神经科,成都610041

出　　处：《磁共振成像》2023年第7期192-196,202,共6页Chinese Journal of Magnetic Resonance Imaging

基　　金：国家自然科学基金(编号:81901712);四川省科技计划重点研发项目(编号:2021YFS0175)。

摘　　要：MRI具有无创、软组织分辨率高、可重复性强等优点,能无创地可视化肌肉形态特征及病理改变,已成为目前肌肉疾病的主要影像检查方法之一。多模态MRI能为肌肉疾病诊断、疗效动态评估、预后预测提供丰富的影像生物标志物。同时,磁共振新技术不断发展,肌肉脂肪替代及水肿等组织特征定量评估方法逐步应用于临床,为肌病临床精准诊断提供新方法。按照临床诊断思路,通常肌病根据肌无力类型可分为六种类型。本文主要根据临床诊断思路,总结不同类型肌病的磁共振表现,并针对磁共振技术在具有选择性受累肌病的组织特征刻画及其鉴别诊断中的应用价值进行全面综述,为临床诊疗提供影像支撑。MRI has the advantages of high soft tissue resolution,non-invasive,great reproducibility,visualizing changes in muscle volume and tissue characteristics,which can be used as the main method for diagnosis and following-up of muscle disease progression.Several previous studies have shown that multimodal MRI can provide multiple imaging biomarkers for the diagnosis,dynamic evaluation of efficacy,prognosis and prediction of muscle diseases.Meanwhile,with the development of new magnetic resonance image technology,quantitative evaluation methods of tissue characteristics such as muscle fat replacement and edema have been gradually applied in clinical practice.According to the types of muscle weakness,muscle diseases can be divided into six types.Therefore,this paper mainly reviews the research progress of the application of MRI in the tissue characterization and differential diagnosis of different muscle diseases based on the characteristics of the six classification modes of muscle diseases,so as to provide image support for clinical diagnosis and treatment.

关 键 词：肌病 肌营养不良 先天性肌病 肌无力 磁共振成像 

分 类 号：R445.2[医药卫生—影像医学与核医学] R685[医药卫生—诊断学]