岩藻黄素降糖活性及其作用机制的研究进展  

Research Progress in Blood Glucose-Lowering Activity and Mechanism of Fucoxanthin

作　　者：李希昊 李佳璇 于德洋 李旺 谭明乾[2,3] 苏文涛 LI Xihao;LI Jiaxuan;YU Deyang;LI Wang;TAN Mingqian;SU Wentao(School of Food Science and Technology,Dalian Polytechnic University,Dalian 116034,Liaoning,China;National Engineering Research Center of Seafood,Dalian Polytechnic University,Dalian 116034,Liaoning,China;Academy of Food Interdisciplinary Science,Dalian Polytechnic University,Dalian 116034,Liaoning,China)

机构地区：[1]大连工业大学食品学院,辽宁大连116034 [2]大连工业大学国家海洋食品工程技术研究中心,辽宁大连116034 [3]大连工业大学食品交叉科学研究院,辽宁大连116034

出　　处：《食品研究与开发》2023年第15期193-200,共8页Food Research and Development

基　　金：国家自然科学基金项目(32222070)。

摘　　要：岩藻黄素是自然界中含量最为丰富的类胡萝卜素,是藻类中重要的营养功效因子。岩藻黄素可以通过抑制碳水化合物水解酶的活性,改善胰岛素信号,上调葡萄糖转运蛋白-4的表达和抑制脂肪细胞因子的产生等方式降低体内血糖水平。该文综述岩藻黄素在藻类细胞中的合成及其在人体内的吸收过程,并详细总结岩藻黄素可能的降糖机制,以期为岩藻黄素降糖机制研究提供借鉴,加速糖尿病等慢性疾病的临床治疗进程。Fucoxanthin is an abundant carotenoid in the nature and an important nutritional factor in algae.Fucoxanthin can reduce the level of blood glucose by inhibiting the activity of carbohydrate hydrolase,improving insulin signal,up-regulating the expression of glucose transporter-4(GLUT4)and inhibiting the production of adipocytokines.The synthesis of fucoxanthin in algae and the absorption of this compound in human body were introduced.Furthermore,the possible blood glucose-lowering mechanisms of fucoxanthin were summarized in detail.The review aims to provide a reference for the relevant research and the clinical treatment of chronic diseases such as diabetes mellitus.

关 键 词：岩藻黄素 类胡萝卜素 降糖活性 作用机制 糖尿病 

分 类 号：TS201.2[轻工技术与工程—食品科学]