母乳低聚糖(HMOs)的科学共识  

Scientific Consensus on Human Milk Oligosaccharides(HMOs)

作　　者：中国食品科学技术学会 The Chinese Institute of Food Science and Technology(Beijing 100048)

机构地区：[1]北京100048

出　　处：《中国食品学报》2023年第6期452-457,共6页Journal of Chinese Institute Of Food Science and Technology

摘　　要：母乳低聚糖(human milk oligosaccharides,HMOs)是母乳中含量第三的固体成分,在支持婴幼儿特征肠道菌群建立和免疫等方面发挥重要作用,其发现、制造与应用对于促进人群健康,尤其在改善婴幼儿健康和营养需求方面具有里程碑式的意义。目前,HMOs已在100余个国家和地区批准和/或上市使用。其生产方式主要以微生物发酵法为主,产品结构与母乳中的HMOs完全一致。相关临床人群实验和动物毒理实验以及多年使用历史均证明其用于婴幼儿配方食品等是安全的。为了促进我国婴幼儿配方食品、特殊医学用途配方食品等领域的高质量发展和产业升级,服务更多消费者营养健康需求,中国食品科学技术学会组织食品科学、临床医学、生物发酵、食品营养等领域专家与产业界代表,通过现场咨询、文献检索和专题研讨等形式,广泛讨论形成对母乳低聚糖的科学共识,以推动HMOs在中国食品行业的合法使用。Human milk oligosaccharides(HMOs)constitute the third most abundant solid component in human milk and play a crucial role in establishing distinctive intestinal flora and bolstering immunity in infants and young children.The discovery,production,and application of HMOs hold significant importance in enhancing the health of certain populations and nutritional requirements,thereby benefiting society's overall well-being.HMOs have received regulatory approval and/or commercial availability in over 100 countries and regions.The primary method employed for their production involves microbial fermentation,resulting in HMO structures that are identical to those found in breast milk.Extensive animal toxicology experiments and clinical trials have confirmed the safety of HMOs for use in infant formula food.To foster industrial progress in the development of high-quality infant formula,food for special medical purposes and other related fields in China,as well as to cater to the nutritional and health needs of a more extensive consumer base,the relevant experts in academic and industrial circles were organized by Chinese Institute of Food Science and Technology to form this consensus after extensive discussions through enquiries,literature retrieval and seminars,which promotes the legal use of HMOs in China's food industry.

关 键 词：母乳低聚糖 生物发酵 营养健康 审批应用 

分 类 号：TS252.1[轻工技术与工程—农产品加工及贮藏工程]