基于化学信息任务驱动的仪器分析实验课程的教学探索  

Exploration of Chemoinformatics in Instrumental Analysis Practical Course by Tasks

作　　者：谢彤[1] 吴亮[2] 康安[1] Xie Tong;Wu Liang;Kang An(The First School of Clinical Medicine,Nanjing University of Chinese Medicine,Nanjing 210023;School of Pharmacy,Nanjing University of Chinese Medicine,Nanjing 210023,China)

机构地区：[1]南京中医药大学第一临床医学院,江苏南京210023 [2]南京中医药大学药学院,江苏南京210023

出　　处：《广东化工》2023年第13期210-212,共3页Guangdong Chemical Industry

基　　金：南京中医药大学本科教育教学改革研究课题(NZYJG2022097)。

摘　　要：化学信息学是一门关注化学数据分析、计算和模型构建的交叉学科领域。随着药物研发和设计领域的快速发展,化学信息学在药学专业中的作用变得越来越重要。本论文旨在探讨化学信息学课程对中医药院校中药学专业和中药学专业的重要作用,探索了化学信息学的核心教学要素。为了推进课程设置综合化和国际化,本文探索性提出基于化学信息任务驱动的仪器分析实验课程教学探索,并给出了相关的教学设计。教学过程中结合问题导向的教学形式,在实验课开始前由老师提出具体问题,让学生利用非正式的学习时间自主学习化学信息相关的软件、各种数据库、数据分析方法、可视化和科学写作方法。最终对课程设计、获得的技能以及学生教学适应性等方面进行了反馈评估。Chemoinformatics is an interdisciplinary field that focuses on the analysis,computation,and model construction of chemical data.With the rapid development of drug discovery and design,chemoinformatics has become increasingly important in the field of pharmaceutical sciences.This paper aims to explore the significant role of chemoinformatics courses in the Chinese medicine specialty and pharmacy specialty in Chinese medicine colleges and universities,as well as to investigate the core teaching elements of chemoinformatics.The paper proposes an exploratory teaching approach based on task-driven instrumental analysis practical course in chemoinformatics and provides relevant teaching designs.In the teaching process,a problem-oriented teaching method is employed,where specific questions are presented before the laboratory session,allowing students to independently learn about software related to chemical information,various databases,data analysis methods,visualization techniques,and scientific writing methods during informal learning time.Finally,feedback evaluations were conducted on course design,acquired skills,and students'adaptability to the teaching approach.

关 键 词：化学信息学 仪器分析实验课 教学探索 

分 类 号：G642.0[文化科学—高等教育学]