Exploring the pathogenesis of idiopathic granulomatous mastitis based on the prolactin theory  

作　　者：Yan Zhang Wen-Di Liu Yan-Jun Chen Han Liu Xiao-Fei Liu 

机构地区：[1]College of Traditional Chinese Medicine,Shandong University of Traditional Chinese Medicine,Jinan 250355,China [2]College of First Clinical Medicine,Shandong University of Traditional Chinese Medicine,Jinan 250355,China [3]Department of Breast and Thyroid Surgery,the First Clinical College of Shandong University of Traditional Chinese Medicine,Jinan 250014,China

出　　处：《Medical Theory and Hypothesis》2023年第1期5-9,共5页医学理论与假说

摘　　要：Prolactin(PRL),as a cytokine,plays a variety of multidirectional roles in immunity and inflammation.An autoimmune condition known as idiopathic granulomatous mastitis(IGM)involves many inflammatory cells and cytokines.PRL links neuroendocrine and immune systems and plays an active role in the inflammatory and immune processes.Based on the theory of PRL and combined with the latest research review at home and abroad,this paper aims to review the mechanism of action of PRL on IGM from the aspects of various inflammatory cells,cytokines and pathways,revealing the influence of PRL theory on IGM and the mechanism of action,so as to effectively control inflammation in the long-term.

关 键 词：PROLACTIN idiopathic granulomatous mastitis IMMUNITY theoretical discussion mechanism of action 

分 类 号：R73[医药卫生—肿瘤]