竹叶粉的食用安全性评价  

Food safety assessment of bamboo leaf powder

作　　者：王东霞 谢静华 袁亚[1,4] 李蕊瑞 刘科亮[5] 吴德举 陈锦瑶[1,2] 张立实 WANG Dongxia;XIE Jinghua;YUAN Ya;LI Ruirui;LIU Keliang;WU Deju;CHEN Jinyao;ZHANG Lishi(West China School of Public Health,West China Fourth Hospital of Sichuan University,Sichuan Chengdu 610041,China;Sichuan Key Laboratory of Food Safety Monitoring and Risk Assessment,Sichuan Chengdu 610041,China;The Third Hospital of Mianyang,Sichuan Mental Health Center,Sichuan Mianyang 621000,China;School of Laboratory Medicine of Chengdu Medical College,Sichuan Chengdu 610500,China;Institute of Toxicology,Sichuan Center for Disease Control and Prevention,Sichuan Chengdu 610041,China;Sichuan Institute of Food Safety,Sichuan Chengdu 610041,China)

机构地区：[1]四川大学华西公共卫生学院,四川大学华西第四医院,四川成都610041 [2]四川省食品安全监测与风险评估重点实验室,四川成都610041 [3]绵阳市第三人民医院·四川省精神卫生中心,四川绵阳621000 [4]成都医学院检验医学院,四川成都610500 [5]四川省疾病预防控制中心毒理检验所,四川成都610041 [6]四川省食品安全学会,四川成都610041

出　　处：《中国食品卫生杂志》2023年第5期717-722,共6页Chinese Journal of Food Hygiene

摘　　要：目的评价竹叶粉的食用安全性。方法通过文献检索、营养成分及活性成分检测、卫生学指标(重金属、农药残留和微生物污染)检测、毒理学安全性评价(急性经口毒性试验、三项遗传毒性试验和90 d经口毒性试验)等多方面综合评估竹叶粉食用安全性。结果竹叶在国内外有悠久的食用和使用历史,未见有中毒和不良反应记载。竹叶样品含有蛋白质等营养成分,总酚含量较高,各项卫生学指标均未超出类似食品限量要求。毒理学安全性评价试验中,竹叶粉未表现出毒性作用,未观察到有害作用剂量为4.0 g/kg·BW。结论竹叶粉摄入剂量低于6 g/d时,对一般成人可能造成的不良健康作用极小。Objective To evaluate the food safety of bamboo leaf powder.Methods The edible safety of bamboo leaf powder was evaluated through a literature review and the following aspects were considered:nutritional composition and active ingredient detection,hygiene indexes(heavy metals,pesticide residues,and microbial contamination)detection,toxicological safety evaluation(acute oral toxicity,three genotoxicity,and 90-day oral toxicity tests).Results Bamboo leaves presented a long history of consumption and use at home and abroad,and no record of poisoning or adverse reactions was found.Bamboo leaf powder contained protein and other nutrients,and a relatively high phenol content.All the sanitary indicators did not exceed the limit requirements of similar foods.The toxicological safety evaluation test showed that bamboo leaf powder had no harmful effects and that its NOAEL was 4.0 g/kg·BW.Conclusion When the dosage of leaf powder is greater than 6 g/d,little adverse health effects may occur in the general adult population.

关 键 词：竹叶粉 竹叶 成分分析 污染物 食品安全 毒理学试验 安全性评估 

分 类 号：R155[医药卫生—营养与食品卫生学]