Regulation of noncoding RNAs in innate lymphoid cells  

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作  者:Benyu Liu Lingwei Zhang Pingping Zhu Zusen Fan 

机构地区:[1]Research Center of Basic Medicine,Academy of Medical Sciences,Zhengzhou University,Zhengzhou 450001,China [2]school of Life Sciences,Zhengzhou University,Zhengzhou 45oo01,China.Key Laboratory of Infection and Immunity of CAS,CAS Center for Excellence in Biomacromolecules,Institute of Biophysics,Chinese Academy of Sciences,Beijing 100101,China [3]University of Chinese Academy of Sciences,Bejing 100049,China

出  处:《Cellular & Molecular Immunology》2023年第5期543-545,共3页中国免疫学杂志(英文版)

基  金:the National Key R&D Program of China(2021YFA1302000,2020YFA0803501);the National Natural Science Foundation of China(32170874,81921003,31930036);Joint Funding of Henan Provincial ScienceandTechnologyR&DPlan(222301420015).

摘  要:Innate lymphoid cells(ILCs)have been defined in recent years and are important effector cells against pathogens and critical regulators in maintaining tissue homeostasis[1].Noncoding RNAs(ncRNAs),such as circular RNAs(circRNAs),long noncoding RNAs(lncRNAs),and microRNAs(miRNAs),in ILCs are emerging and have been described to function in ILC biology.These ncRNAs are distributed with unique patterns in ILCs and function in different molecular mechanisms.Accumulating research evidence demonstrates that ncRNA dysregulation links ILC-mediated immune responses and diseases.

关 键 词:LYMPHOID HOMEOSTASIS noncoding 

分 类 号:R392[医药卫生—免疫学]

 

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