Rhabdomyolysis-induced acute kidney injury after administration of a red yeast rice supplement:A case report  

作　　者：Ya-Han Wang Si-Shuo Zhang Hai-Tao Li Hong-Wei Zhi Hong-Yun Wu 

机构地区：[1]Department of Neurology,Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Jinan 250014,Shandong Province,China

出　　处：《World Journal of Clinical Cases》2023年第23期5547-5553,共7页世界临床病例杂志

基　　金：Supported by the Natural Science Foundation of Shandong Province,No.ZR2021QH110.

摘　　要：BACKGROUND A few reports have revealed induction of rhabdomyolysis by a red yeast rice(RYR)supplement or by RYR in combination with abiraterone(an androgen biosynthesis inhibitor).CASE SUMMARY A 76-year-old man presented with progressive limb weakness,muscle soreness,and acute kidney injury(AKI).He had been taking the anti-prostate cancer drug abiraterone for 14 mo and had added a RYR supplement 3 mo before symptom onset.After being diagnosed with rhabdomyolysis-induced AKI,the patient discontinued these drugs and responded well to hemodialysis and hemoperfusion.After 23 d of treatment,creatine kinase levels returned to normal and serum creatinine levels decreased.CONCLUSION We speculate that statins,the main lipid-lowering component of RYR,or a combination of statins and abiraterone,will increase the risk of rhabdomyolysis.

关 键 词：RHABDOMYOLYSIS Acute kidney injury LOVASTATIN ABIRATERONE Case report 

分 类 号：R595[医药卫生—内科学] R692[医药卫生—临床医学]