ABIRATERONE

作品数：27被引量：30H指数：3
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相关作者：周晨旭牛朝诗更多>>
相关机构：安徽省立医院更多>>
相关期刊：《Cancer Biology & Medicine》《Asian Journal of Urology》《Open Journal of Urology》《药学进展》更多>>
相关基金：国家自然科学基金上海市自然科学基金更多>>
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Clinical Exploration of Immunosuppressants Combined with Abiraterone in the Treatment of Metastatic Castration-Resistant Prostate Cancer
《Journal of Clinical and Nursing Research》2024年第5期124-128,共5页Lin Ma 
Prostate cancer is a malignant tumor with a high incidence in elderly men.In recent years,with the improvement of people’s living standards and the advancement of detection technology,the incidence of prostate cancer...
关键词：IMMUNOSUPPRESSANTS ABIRATERONE Prostate cancer Immune system 
Rhabdomyolysis-induced acute kidney injury after administration of a red yeast rice supplement:A case report
《World Journal of Clinical Cases》2023年第23期5547-5553,共7页Ya-Han Wang Si-Shuo Zhang Hai-Tao Li Hong-Wei Zhi Hong-Yun Wu 
Supported by the Natural Science Foundation of Shandong Province,No.ZR2021QH110.
BACKGROUND A few reports have revealed induction of rhabdomyolysis by a red yeast rice(RYR)supplement or by RYR in combination with abiraterone(an androgen biosynthesis inhibitor).CASE SUMMARY A 76-year-old man presen...
关键词：RHABDOMYOLYSIS Acute kidney injury LOVASTATIN ABIRATERONE Case report 
High IL-23^(+)cells infiltration correlates with worse clinical outcomes and abiraterone effectiveness in patients with prostate cancer被引量：2
《Asian Journal of Andrology》2022年第2期147-153,共7页Zheng Liu Jun-Yu Zhang Yun-Jie Yang Kun Chang Qi-Feng Wang Yun-Yi Kong Bo Dai 
This study was supported by grant from the National Key R&D Program of China(2017YFC0114303);grant from the Natural Science Foundation of Science and Technology Commission of Shanghai Municipality(20ZR1412300);grant from the Medical Innovation Research Project of the Science and Technology Commission of Shanghai Municipality(No.20Y11905000);grants from the AoXiang Project of the Shanghai Anti-Cancer Association(SACA-AX201908 and SACA-AX202005);All these study sponsors have no roles in the study design,collection,analysis,and interpretation of data.
Individualized treatment of prostate cancer depends on an accurate stratification of patients who are sensitive to various treatments.Interleukin-23(IL-23)was reported to play a significant role in prostate cancer.Her...
关键词：abiraterone acetate INTERLEUKIN-23 prognosis prostate cancer 
Predictors of efficacy of corticosteroid switching from abiraterone plus prednisone to dexamethasone in patients with metastatic castration-resistant prostate cancer被引量：1
《Asian Journal of Andrology》2022年第2期154-160,共7页Yu-Chao Ni Jin-Ge Zhao Meng-Ni Zhang Yi-Jun Zhang Zhen-Yu Yang Ni Chen Jun-Ru Chen Peng-Fei Shen Guang-Xi Sun Xing-Ming Zhang Yong-Hong Li Hao Zeng 
This work was supported by the Natural Science Foundation of China(NSFC,No.81672547,81872107,81872108,81972502,81902577,and 81902577);1.3.5 project for disciplines of excellence,West China Hospital,Sichuan University(No.0040205301E21);the Research Foundation for the Postdoctoral Program of Sichuan University(2021SCU12014);Postdoctoral Research Project,West China Hospital,Sichuan University(20HXBH026).
Corticosteroid switching can reverse abiraterone resistance in some patients with metastatic castration-resistant prostate cancer(mCRPC).Here,we investigated the potential biomarkers for predicting the efficacy of cor...
关键词：abiraterone acetate alkaline phosphatase corticosteroid switching DEXAMETHASONE metastatic castration-resistant prostate cancer 
Early Evaluation of PSA Response in Metastatic Prostate Cancer Treated with Abiraterone
《Open Journal of Urology》2021年第7期251-263,共13页Ana Santafé-Jiménez Virginia Morillo-Macías Angel Sánchez-Iglesias Encarnación Fernández-Camacho Carlos Ferrer-Albiach 
Background: According to the main prostate cancer guidelines, the response to treatment with abiraterone plus prednisone (AA+P) must be evaluated by assessing prostate-specific antigen (PSA) levels at...
关键词：Prostate Cancer ABIRATERONE Prostate-Specific Antigen Decline SURVIVAL 
Response of prostate cancer to addition of dutasteride after progression on abiraterone
《Asian Journal of Andrology》2021年第2期222-223,共2页Jian-Po Lian Yuan-Yuan Gao Jing-Jie Tang Xi Chen Ying Liu Deng-Long Wu Zhen-Fei Li Sheng-Song Huang 
This research was partially funded by the National Key R&D program of China(2018YFA0508200 to ZFL);Clinical Innovations of Shanghai SHENKANG(SHDC12019112 to DLW);the Strategic Priority Research Program of Chinese Academy of Sciences(XDB19000000 and XDA12010318 to ZFL);the National Natural Science Foundation of China(81672526 to DLW and 81872075 to JJT);the Prostate Cancer Foundation Young Investigator Award(#15YOUN11 to ZFL).
Dear Editor,Abiraterone has achieved great success in clinic by targeting cytochrome P45017A1(CYP17A)for prostate cancer therapy.1,2 However,drug resistance is inevitable and novel strategy is urgently required.Our pr...
关键词：ABIRATERONE CYP17 cancer 
Overcoming the mechanisms of primary and acquired resistance to new generation hormonal therapies in advanced prostate cancer: focus on androgen receptor independent pathways
《Cancer Drug Resistance》2020年第4期726-741,共16页Maristella Bungaro Consuelo Buttigliero Marcello Tucci 
In recent years,many therapeutic advances have been made in the management of castration-resistant prostate cancer,with the development and approval of many new drugs.The androgen receptor(AR)is the main driver in pro...
关键词：castration-resistant prostate cancer androgen receptor signalling hormonal treatment enzalutamide ABIRATERONE resistance mechanisms 
Systemic treatment for metastatic prostate cancer被引量：2
《Asian Journal of Urology》2019年第2期162-168,共7页Gwenaelle Gravis 
The management of metastatic prostate cancer(mPCa)has changed over the past ten years.Several new drugs have been approved with significant overall survival benefits in metastatic castration resistant prostate cancer(...
关键词：Prostate cancer Metastatic prostate cancer Castrate sensitive metastatic prostate cancer ABIRATERONE DOCETAXEL 
Clinical activity of abiraterone plus prednisone in docetaxel-naive and docetaxel-resistant Chinese patients with metastatic castration-resistant prostate cancer被引量：2
《Asian Journal of Andrology》2019年第2期131-136,共6页Guo-Wen Lin Gao-Xiang Li Bo Dai Ding-Wei Ye Yun-Yi Kong Yue Wang Yi-Jun Shen 
the National Natural Science Foundation(No.81702535,81572531);Natural Science Foundation of Shanghai Municipality(No.16ZR1406500);Outstanding Young Talent Training Plan of Shanghai Municipal Commission of Health and Family Planning(No.XYQ2013102).
This study investigated the clinical activity of abiraterone plus prednisone in docetaxel-naive and docetaxel-resistant Chinese patients with metastatic castratio n-resista nt prostate can cer(mCRPC).A total of 146 pa...
关键词：ABIRATERONE ACETATE CASTRATION-RESISTANT prostate cancer clinical activity docetaxel-naive docetaxel-pretreated 
Potential impact of combined inhibition of 3a-oxidoreductases and 5a-reductases on prostate cancer被引量：2
《Asian Journal of Urology》2019年第1期50-56,共7页Michael V.Fiandalo Daniel T.Gewirth James L.Mohler 
This study was supported by the DoD Prostate Cancer Research Program Award(No.W81XWH-16-1-0635);the National Cancer Institute(NO.P01CA77739 and NO.R21CA205108)to James L.Mohler;Post-doctoral Training Award(No.W81XWH-15-1-0409)to Michael V.Fiandalo;DoD Synergistic Idea Development Award(No.W81XWH-14-1-0520)to Dan T.Gewirth;NCI Cancer Center Support Grant to Roswell Park Comprehensive Cancer Center for the Bioanalytics,Metabolomics and Pharmacokinetics,Pathology Network,and Genomics Shared Resources(No.P30CA016056).
Prostate cancer(PCa)growth and progression rely on the interaction between the androgen receptor(AR)and the testicular ligands,testosterone and dihydrotestosterone(DHT).Almost all men with advanced PCa receive androge...
关键词：Androstanediol DIHYDROTESTOSTERONE DUTASTERIDE 3a-oxidoreductases Androgen deprivation therapy ABIRATERONE 
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