Background The aim of this study was to assess the effect of a 4-week dutasteride treatment on reducing the intraoperative and postoperative bleeding,as well as the amount and duration of irrigation required to clear ...
Background Only a few reports have currently studied the efficacy of dutasteride in patients with small benign prostatic hyperplasia(BPH).We investigated the efficacy of dutasteride on reducing lower urinary tract sym...
For the article entitled"Efficacy of a combination of dutasteride,tadalafil,and solifenacin in the treatment of previously unsuccessful patients"[Asian J Urol 9(2022)42-50,D0l:https://doi.org/10.1016/j.ajur.2021.04.00...
Objective Bleeding is one of the most common complications of transurethral resection of the prostate(TURP).Several previous studies reported that administering dutasteride before surgery could reduce perioperative bl...
Objective To evaluate the efficacy and safety of simultaneous administration of dutasteride,tadalafil and solifenacin in the treatment of benign prostatic hyperplasia(BPH)with overactive bladder symptoms and lower uri...
This research was partially funded by the National Key R&D program of China(2018YFA0508200 to ZFL);Clinical Innovations of Shanghai SHENKANG(SHDC12019112 to DLW);the Strategic Priority Research Program of Chinese Academy of Sciences(XDB19000000 and XDA12010318 to ZFL);the National Natural Science Foundation of China(81672526 to DLW and 81872075 to JJT);the Prostate Cancer Foundation Young Investigator Award(#15YOUN11 to ZFL).
Dear Editor,Abiraterone has achieved great success in clinic by targeting cytochrome P45017A1(CYP17A)for prostate cancer therapy.1,2 However,drug resistance is inevitable and novel strategy is urgently required.Our pr...
supported by the National Research Foundation of Ko-rea(NRF);funded by the Korean government(MSIP)(No.2009-0083533)
The aim of this study was to optimize a tablet formulation of dutasteride that is bioequivalent to a commercially available soft gelatin capsule(Avodart~?). The effect of cyclodextrin on enhancing the aqueous solubili...
Background: Transurethral resection of prostate (TURP) is the gold standard in the surgical treatment of symptomatic benign prostatic hyperplasia (BPH). Blood loss is one of the most common complications of TURP. Obje...
This study was supported by the DoD Prostate Cancer Research Program Award(No.W81XWH-16-1-0635);the National Cancer Institute(NO.P01CA77739 and NO.R21CA205108)to James L.Mohler;Post-doctoral Training Award(No.W81XWH-15-1-0409)to Michael V.Fiandalo;DoD Synergistic Idea Development Award(No.W81XWH-14-1-0520)to Dan T.Gewirth;NCI Cancer Center Support Grant to Roswell Park Comprehensive Cancer Center for the Bioanalytics,Metabolomics and Pharmacokinetics,Pathology Network,and Genomics Shared Resources(No.P30CA016056).
Prostate cancer(PCa)growth and progression rely on the interaction between the androgen receptor(AR)and the testicular ligands,testosterone and dihydrotestosterone(DHT).Almost all men with advanced PCa receive androge...
Erectile dysfunction is a common side effect of finasteride and dutasteride treatments. The objective of this study was to investigate the structural changes in the penis using a benign prostatic hyperplasia (BPH) r...