Perspectives in human brain plasticity sparked by glioma invasion:from intraoperative(re)mappings to neural reconfigurations  

作　　者：Sam Ng Hugues Duffau Guillaume Herbet 

机构地区：[1]Department of Neurosurgery,Gui de Chauliac Hospital,Montpellier University Medical Center,Montpellier,France [2]Institute of Functional Genomics,University of Montpellier,CNRS,INSERM,Montpellier,France [3]Praxiling Laboratory,UMR5267,CNRS,Paul Valéry-Montpellier 3 University,Montpellier,France

出　　处：《Neural Regeneration Research》2024年第5期947-948,共2页中国神经再生研究（英文版）

摘　　要：Exploring the aptitude of the human brain to compensate functional consequences of a lesion damaging its structural architecture is a key challenge to improve patient care in various neurological diseases,to optimize neuroscientifically-informed strategies of postlesional rehabilitation,and ultimately to develop innovative neuro-regenerative therapies.The term‘plasticity’,initially referring to the intrinsic propensity of neurons to modulate their synaptic transmission in a learning situation,was progressively transposed to brain injury research and clinical neurosciences.Indeed,in the event of brain damage,adaptive mechanisms of compensation allow a partial reshaping of the structure and activities of the central nervous system,thus permitting to some extent the maintenance of brain functions.

关 键 词：PLASTICITY figuration consequences 

分 类 号：R739.41[医药卫生—肿瘤]