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作 者:Nabin Koirala Abdulnasir Hossen Ioannis U.Isaias Jens Volkmann Muthuraman Muthuraman
机构地区:[1]Child Study Center,School of Medicine,Yale University,New Haven,CT,USA [2]Department of Electrical&Computer Engineering,Sultan Qaboos University,Al-Khod,Muscat,Oman [3]Neural Engineering with Signal Analytics and Artificial Intelligence,Department of Neurology,University Hospital of Würzburg,Würzburg,Germany [4]Centro Parkinson e Parkinsonism,Azienda Socio Sanitaria Territoriale G.Pini-CTO,20126 Milan,Italy
出 处:《Neural Regeneration Research》2024年第5期977-978,共2页中国神经再生研究(英文版)
基 金:supported by the Deutsche Forschungsgemeinschaft(DFG,German Research Foundation)Project-ID 424778381-TRR 295(to MM);the Fondazione Grigioni per il Morbo di Parkinson(to IUI).
摘 要:Tremor occurs in about half of multiple sclerosis(MS)patients.MS tremor has a broad frequency range of 2.5-7 Hz,with a higher prevalence of postural tremor(44%)compared to intentional tremor(6%)(Alusi et al.,2001).Tremor may affect the upper and lower extremities,head,and trunk,and may even affect the vocal cords in isolated cases of palatal tremor.MS tremor is classically attributed to lesions of the brain stem,cerebellum,or cerebellar peduncles,and tremor intensity has been shown to correlate with the number of lesions or their functional connections.However,recent work has demonstrated that inflammatory damage to the cerebello-thalamic and cortico-thalamic pathways might also play an important role in causing tremor,as it co-occurs with other signs and symptoms of MS such as dysarthria,dysmetria,dysdiadochokinesia,and dystonia(Alusi et al.,2001).
分 类 号:R744.51[医药卫生—神经病学与精神病学]
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