抗冻蛋白多维活性表征鉴定新进展  

Recent progress in the characterization of multidimensional activities of antifreeze proteins

作　　者：单妍妍 廖丽 胥义[1] 陈波 Shan Yanyan;Liao Li;Xu Yi;Chen Bo(School of Health Science and Engineering,University of Shanghai for Science and Technology,Shanghai 200093,China;Key Laboratory of Polar Science,MNR,Polar Research Institute of China,Shanghai 200136,China)

机构地区：[1]上海理工大学,健康科学与工程学院,上海200093 [2]中国极地研究中心(中国极地研究所),自然资源部极地科学重点实验室,上海200136

出　　处：《极地研究》2023年第3期490-497,共8页Chinese Journal of Polar Research

基　　金：国家重点研发计划(2018YFC1406702)资助。

摘　　要：抗冻蛋白(antifreeze protein)是一类能够控制冰晶、帮助生物免受低温损害的蛋白,具有多种优良的抗冻活性。本文全面讨论了抗冻蛋白多种抗冻活性(冰面结合活性、热滞活性、重结晶抑制活性、冰晶修饰活性和冰粘附活性),介绍了抗冻活性鉴定方法及其最新的进展。在此基础上,总结了抗冻蛋白研究存在的问题与挑战,并对其研究前景进行了展望。Antifreeze proteins(AFPs)are proteins with a variety of activities that inhibit ice crystal growth and protect organisms from low-temperature damage.In this review,we described several activities of AFPs including ice adsorption,thermal retardation,recrystallization inhibition,ice crystal morphology modification and ice adhesion activities.Furthermore,we summarized specific methodologies and current advances in AFP characterization.Finally,we discussed remaining issues,challenges,and future directions in AFP research.

关 键 词：抗冻蛋白 冰面结合 热滞活性 重结晶抑制 冰晶修饰 

分 类 号：Q51[生物学—生物化学]