Global trends and hotspots of treatment for nonalcoholic fatty liver disease:A bibliometric and visualization analysis(2010-2023)  

作　　者：Jin-Jin Dai Ya-Fei Zhang Zhen-Hua Zhang 

机构地区：[1]Department of Infectious Diseases,Suzhou Hospital of Anhui Medical University,Suzhou 234000,Anhui Province,China [2]Department of Infectious Diseases,The Second Affiliated Hospital of Anhui Medical University,Hefei 230601,Anhui Province,China

出　　处：《World Journal of Gastroenterology》2023年第37期5339-5360,共22页世界胃肠病学杂志（英文版）

基　　金：National Science Foundation of China,No.81273142;Anhui Provincial Natural Science Foundation,No.2108085MH298;University Scientific Research Project of Anhui Provincial Education Department,No.KJ2021A0323;Fund of Anhui Medical University,No.2021xkj196;Clinical Medicine project of Anhui Medical University,No.2021LCXK027;The Second Hospital of Anhui Medical University Natural Science Foundation,No.2019GMFY02。

摘　　要：BACKGROUND Nonalcoholic fatty liver disease(NAFLD)is chronic,with its progression leading to liver fibrosis and end-stage cirrhosis.Although NAFLD is increasingly common,no treatment guideline has been established.Many mechanistic studies and drug trials have been conducted for new drug development to treat NAFLD.An up-to-date overview on the knowledge structure of NAFLD through bibliometrics,focusing on research hotspots,is necessary to reveal the rational and timely directions of development in this field.AIM To research the latest literature and determine the current trends in treatment for NAFLD.METHODS Publications related to treatment for NAFLD were searched on the Web of Science Core Collection database,from 2010 to 2023.VOSviewers,CiteSpace,and R package“bibliometrix”were used to conduct this bibliometric analysis.The key information was extracted,and the results of the cluster analysis were based on network data for generating and investigating maps for country,institution,journal,and author.Historiography analysis,bursts and cluster analysis,cooccurrence analysis,and trend topic revealed the knowledge structure and research hotspots in this field.GraphPad Prism 9.5.1.733 and Microsoft Office Excel 2019 were used for data analysis and visualization.RESULTS In total,10829 articles from 120 countries(led by China and the United States)and 8785 institutions were included.The number of publications related to treatment for NAFLD increased annually.While China produced the most publications,the United States was the most cited country,and the United Kingdom collaborated the most from an international standpoint.The University of California-San Diego,Shanghai Jiao Tong University,and Shanghai University of Traditional Chinese Medicine produced the most publications of all the research institutions.The International Journal of Molecular Sciences was the most frequent journal out of the 1523 total journals,and Hepatology was the most cited and co-cited journal.Sanyal AJ was the most cited author,the most co-

关 键 词：BIBLIOMETRICS TREATMENT Therapy Nonalcoholic fatty liver disease Metabolic dysfunction-associated fatty liver disease Historiography analysis 

分 类 号：R575.5[医药卫生—消化系统]