Explore the nucleolus: unveiling the hidden layer with superresolution microscopy  

作　　者：Rongfei Wei Xinyu Wang Dong Li 

机构地区：[1]National Laboratory of Biomacromolecules,CAS Center for Excellence in Biomacromolecules,Institute of Biophysics,Chinese Academy of Sciences,Beijing 100101,China [2]College of Life Sciences,University of Chinese Academy of Sciences,Beijing 100049,China

出　　处：《Science China(Life Sciences)》2023年第9期2193-2195,共3页中国科学（生命科学英文版）

摘　　要：The nucleolus, a well-known membraneless organelle and the largest substructure with the highest transcriptional activity in the nucleus, was discovered over 200 years ago and is best known for its critical role in ribosome biogenesis(Kresoja-Rakic and Santoro, 2019;Navarro, 2019). Previous studies have reported that the nucleolus comprises three radially distributed layers known as the fibrillar center (FC).

关 键 词：TRANSCRIPTIONAL ORGANELLE resolution 

分 类 号：Q243[生物学—细胞生物学]