Commentary: A nearly forgotten class of anti-inflammatory lipid molecules in central nervous system  

作　　者：Nan Ru Wan-Yang Sun Hua-Jun Wang Yan-Ping Wu Xiao-Fei Zheng Rong-Rong He 

机构地区：[1]The First Affiliated Hospital/International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education(MOE)/Guangdong Engineering Research Center of Chinese Medicine&Disease Susceptibility/Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research,Jinan University,Guangzhou 510632,China [2]State Key Laboratory of Quality Research in Chinese Medicine,Macao University of Science and Technology,Macao,China

出　　处：《Acta Pharmaceutica Sinica B》2023年第6期2809-2811,共3页药学学报（英文版）

基　　金：supported, in part, by Natural Science Foundation of China (grant numbers 82125038 and 82004231);Natural Science Foundation of Guangdong (grant number 2021B1515120023, China);the Local Innovative and Research Teams Project of Guangdong Pearl River Talents Program (grant number 2017BT01Y036, China);GDUPS (2019, China);the Innovation Team Project of Guangdong Provincial Department of Education (2020KCXTD003, China);Guangdong Basic and Applied Basic Research Fund (grant number 2020A1515110388, China)。

摘　　要：Lipids are the major components of cells in the central nervous system(CNS) and are essential for the brain development and homeostasis. Several studies have demonstrated that impaired lipid metabolism is closely related to neurological diseases among the elderly^(1). Lipidomics can serve us well in identifying and quantifying lipid molecules in cells, tissues, and organisms at the system level. However, finding out biologically meaningful lipids from the massive lipidomics data is not straightforward.

关 键 词：LIPIDOMICS Aging 3-Sulfogalactosyl diacylglycerols ANTI-INFLAMMATION Central nervous system 

分 类 号：R338[医药卫生—人体生理学]