Bruch膜开口-最小盘沿宽度在开角型青光眼中的应用  

Application of Bruch's membrane opening minimum rim width in open-angle glaucoma

作　　者：张迪(综述) 张水华[1] 肖铮[1] 李元媛(审校)[1] ZHANG Di;ZHANG Shuihua;XIAO Zheng;ZHANG Yang;LI Yuanyuan(Harbin Medical University,the Second Affiliated Hospital of Harbin Medical University,Harbin 150000,China)

机构地区：[1]哈尔滨医科大学附属第二医院,哈尔滨150000

出　　处：《眼科学报》2023年第7期526-534,共9页Eye Science

基　　金：黑龙江省博士后资助项目(LBH-Z17112)。

摘　　要：青光眼是全球首位不可逆性致盲眼病,该疾病与进行性视网膜神经节细胞凋亡相关,大多数患者在视功能改变之前视盘结构已经发生改变,检测视盘R结构改变对于早期青光眼的诊断至关重要。近几年新视盘参数Bruch膜开口-最小盘沿宽度(Bruch's membrane opening minimum rim width,BMO-MRW)在临床上应用越来越广泛,成为目前临床研究的一个热点参数。众所周知视网膜神经纤维层(retinal nerve fiber layer,RNFL)具有很好的青光眼诊断能力,很多研究表明BMO-MRW与RNFL具有相似的诊断性能,并在近视性、异常视盘等一些视盘结构不清晰的青光眼中,BMO-MRW的诊断能力优于RNFL,该参数在监测青光眼病情变化方面也起到一定作用。也有研究表明该参数对青光眼术后随访的应用可能受到一定限制。该文对BMO-MRW在开角型青光眼的诊断及随访中的临床应用加以综述,供临床同道参考。Glaucoma is the leading cause for irreversible blindness in the world,which is associated with progressive retinal ganglion cell apoptosis.The changes in optic disc structure have been found before visual function variation in many patients.Detecting changes in the structure of the optic disc R is crucial for the diagnosis of early glaucoma.Recently,a new optic disc parameter,Bruce's membrane opening minimum rim width(BMO-MRW),has been increasingly widely used in clinical practice and become a popular parameter in current clinical research.Retinal nerve fiber layer(RNFL)is an important diagnostic indicator for glaucoma.Many studies indicated that BMO-MRW and RNFL have similar diagnostic performance.In some glaucoma cases with unclear optic disc structure,such as myopia and abnormal optic disc,BMO-MRW provides better diagnostic parameter than RNFL does.It also plays a role in monitoring the changes of glaucoma.Some studies also stated the limitation of the application of this parameter in glaucoma postoperative follow-up.This artice reviews the clinical application of BMO-MRW in diagnosis and follow-up of open-angle glaucoma,providing reference for clinical practicers.

关 键 词：开角型青光眼 Bruch膜开口-最小盘沿宽度 视网膜神经纤维层 

分 类 号：R775[医药卫生—眼科]