慢性牙周炎患者和牙周健康人唾液微生物多样性研究及临床意义  

Study on Salivary Microbial Diversity in Patients with Chronic Periodontitis and HealthyPeriodontal Individuals and Its Clinical Significance

作　　者：薛魁 XUE Kui(Department of Stomatology,the Second Affiliated Hospital of Bengbu Medical College,Bengbu 233000,China)

机构地区：[1]蚌埠医学院第二附属医院口腔科,安徽蚌埠233000

出　　处：《工业微生物》2023年第5期51-53,共3页Industrial Microbiology

摘　　要：慢性牙周炎是一种常见的口腔疾病,其主要症状为牙周组织发炎和牙周袋,会导致牙齿松动甚至脱落。过去研究已经发现牙周炎与口腔微生物群落失衡密切相关。唾液是口腔中重要的微生物媒介,可以反映口腔微生物群落的特征。因此,研究慢性牙周炎患者与牙周健康人唾液微生物多样性的差异,对于深入了解慢性牙周炎的发病机制、个体化治疗及预防和促进口腔健康具有重要意义。文章针对慢性牙周炎患者与牙周健康人唾液微生物多样性的差异及其临床意义展开研究,以期为临床医生进行相关治疗提供参考。Chronic periodontitis is a common oral disease,characterized by inflammation of periodontal tissue and periodontal pockets,leading to tooth loosening and even detachment.In previous studies,it has been found that periodontitis is closely related to the imbalance of oral microbiota.Saliva is an important mediator of the oral microbiome,which can reflect the characteristics of the oral microbiota.Therefore,studying the differences in saliva microbial diversity between patients with chronic periodontitis and healthy individuals is of great significance for a deeper understanding of the pathogenesis of chronic periodontitis,personalized treatment,and prevention and promotion of oral health.The paper focuses on the differences in saliva microbial diversity between patients with chronic periodontitis and healthy individuals with periodontitis,and their clinical significance,in order to provide treatment references for clinical doctors.

关 键 词：慢性牙周炎患者 唾液 微生物多样性 临床意义 

分 类 号：R781.42[医药卫生—口腔医学]