Role of lymphotoxin alpha as a new molecular biomarker in revolutionizing tear diagnostic testing for dry eye disease  

作　　者：Chao-Ran Li 

机构地区：[1]Tianjin Medical University Eye Hospital,Tianjin 310011,China

出　　处：《International Journal of Ophthalmology(English edition)》2023年第11期1883-1889,共7页国际眼科杂志（英文版）

摘　　要：Dry eye disease(DED),primarily classified as multifactorial ocular surface disorder,afflicts tens of millions of individuals worldwide,adversely impacting their quality of life.Extensive research has been conducted on tear film analysis over the past decades,offering a range of tests to evaluate its volume,health,and integrity.Yet,early diagnosis and effective treatment for DED continue to pose significant challenges in clinical settings.Nevertheless,by recognizing key phenomena in DED such as ocular surface inflammation,hyperosmolarity,and tear film instability,this article provides a comprehensive overview of both traditional and recently developed methods for diagnosing and monitoring DED.The information serves as a valuable resource not only for clinical diagnosis but also for further research into DED.

关 键 词：dry eye disease tear film BIOMARKER matrix metalloproteinase 9 lymphotoxin alpha 

分 类 号：R773.9[医药卫生—眼科] R758.63[医药卫生—临床医学]