Research progress of ginger in the treatment of gastrointestinal tumors  

作　　者：Guo-Qing Chen Yi Nan Shi-Cong Huang Na Ning Yu-Hua Du Dou-Dou Lu Ya-Ting Yang Fan-Di Meng Ling Yuan 

机构地区：[1]College of Pharmacy,Ningxia Medical College,Yinchuan 750004,Ningxia Hui Autonomous Region,China [2]Key Laboratory of Ningxia Ethnomedicine Modernization,Ministry of Education,Ningxia Medical University,Yinchuan 750004,Ningxia Hui Autonomous Region,China [3]Traditional Chinese Medicine College,Ningxia Medical University,Yinchuan 750004,Ningxia Hui Autonomous Region,China [4]School of Clinical Medicine College,Ningxia Medical University,Yinchuan 750004,Ningxia Hui Autonomous Region,China

出　　处：《World Journal of Gastrointestinal Oncology》2023年第11期1835-1851,共17页世界胃肠肿瘤学杂志（英文版）（电子版）

基　　金："Young Scholars of Western China"(Class A)_West Light Foundation of the Chinese Academy of Sciences,No.XAB2019AW13;Ningxia Natural Science Foundation,No.2022AAC02039.

摘　　要：Cancer seriously endangers human health.Gastrointestinal cancer is the most common and major malignant tumor,and its morbidity and mortality are gradually increasing.Although there are effective treatments such as radio-therapy and chemotherapy for gastrointestinal tumors,they are often accom-panied by serious side effects.According to the traditional Chinese medicine and food homology theory,many materials are both food and medicine.Moreover,food is just as capable of preventing and treating diseases as medicine.Medicine and food homologous herbs not only have excellent pharmacological effects and activities but also have few side effects.As a typical medicinal herb with both medicinal and edible uses,some components of ginger have been shown to have good efficacy and safety against cancer.A mass of evidence has also shown that ginger has anti-tumor effects on digestive tract cancers(such as gastric cancer,colorectal cancer,liver cancer,laryngeal cancer,and pancreatic cancer)through a variety of pathways.The aim of this study is to investigate the mechanisms of action of the main components of ginger and their potential clinical applications in treating gastrointestinal tumors.

关 键 词：GINGER Medicine and food homology Gastrointestinal cancer Molecular mechanism TUMOR 

分 类 号：R735[医药卫生—肿瘤]