臭氧治疗在改善阴道炎阴道微生态环境中的应用  

Application of Ozone Therapy in Improving Vaginal Microecological Environment of Vaginitis

作　　者：万蕊星 贾学玲[2] 袁月 付小明 胡俊平[2] WAN Rui-xing;JIA Xue-ling;YUAN Yue;FU Xiao-ming;HU Jun-ping(School of Nursing,Lanzhou University,Lanzhou 730030,China;Reproductive Medicine Center,The First Hospital of Lanzhou University,Lanzhou 730000,China)

机构地区：[1]兰州大学护理学院,730030 [2]兰州大学第一医院生殖医学中心

出　　处：《国际妇产科学杂志》2023年第6期623-626,共4页Journal of International Obstetrics and Gynecology

基　　金：兰州大学第一医院院内基金(ldyyyn2020-26)。

摘　　要：臭氧是一种强氧化性气体,具有杀菌抗炎作用,已在皮肤、关节和口腔等疾病的治疗中取得一定疗效。阴道炎是临床常见的发病率和复发率都较高的妇科疾病,其临床药物治疗效果不佳,将臭氧治疗应用于阴道炎患者的治疗过程中,能够通过发挥臭氧强大的氧化作用和刺激细胞因子生成,杀灭阴道致病微生物,加速炎症细胞的消散,同时发挥其营养特性,促进阴道黏膜细胞的再生,并加强阴道局部免疫力,恢复阴道正常pH值,重建阴道内环境稳态。但是,目前临床上尚未对臭氧治疗阴道炎的浓度、剂量、时间、随访时间以及臭氧性状的选择等形成统一的规范,如何针对性地根据患者病情选择合适的治疗方案、发挥臭氧治疗的最佳疗效将成为未来臭氧治疗推广和应用的关键。Ozone is a strong oxidizing gas,with bactericidal and anti-inflammatory effects,which has shown certain efficacy in the treatment of skin,joint and oral diseases.Vaginitis is a common gynecological disease with high clinical incidence and recurrence rate,and the clinical efficacy of drug treatment for vaginitis is unsatisfactory.The application of ozone therapy in the treatment process of vaginitis patients can kill vaginal pathogenic microorganisms by exerting the powerful oxidation effect of ozone and stimulating the generation of cytokines,accelerating the dissipation of inflammatory cells.It can also exert its nutritional properties of ozone,promoting the regeneration of vaginal mucosa cell and strengthen the local immunity of the vagina,restore the normal pH of the vagina,and rebuild the homeostasis of the vaginal environment.However,at present,there is no unified standard for the concentration,dosage,duration,follow-up period and selection of ozone properties in the treatment of vaginitis with ozone therapy.How to select the appropriate treatment plan according to the patient′s condition and play the best effect of ozone therapy will become the key to the promotion and application of ozone therapy in the future.

关 键 词：臭氧 阴道炎 微生物学 生态失调 乳杆菌属 

分 类 号：R711.31[医药卫生—妇产科学]