体外诊断技术在原发不明肿瘤诊断中的应用与展望  

Application and prospect of the in vitro diagnostic techniques in the diagnosis of cancer ofunknown primary

作　　者：包雯 BAO Wen(Center For Medical Device Evaluation,National Medical Products Administration,Beijing,China,100081)

机构地区：[1]国家药品监督管理局医疗器械技术审评中心,北京100081

出　　处：《分子诊断与治疗杂志》2023年第10期1841-1845,共5页Journal of Molecular Diagnostics and Therapy

摘　　要：原发不明肿瘤(CUP)是一类经过全面检查仍未找到组织起源的转移性肿瘤。CUP具有强侵袭性,易发生早期转移和预后不佳等特点。随着体外诊断技术的发展,肿瘤组织起源基因检测可准确判断肿瘤的原发灶,有助于优化CUP患者的治疗方案和改善预后。本文就体外诊断技术在CUP诊断中的应用与展望进行综述。Cancer of unknown primary(CUP)is a metastatic tumor with an unidentifiable tissue of origin after a comprehensive examination.CUP has the characteristics of strong invasiveness,prone to early metastasis,and poor prognosis.With the development of in vitro diagnostic technology,tumor tissue of origin tests could accurately determine the primary site of the tumor,which is helpful to optimize the treatment op-tions and improve the prognosis.This review presents the application and the prospect of in vitro diagnostic technology in the diagnosis of CUP.

关 键 词：原发不明肿瘤 组织起源 基因表达谱 体外诊断 

分 类 号：R730.4[医药卫生—肿瘤]