“Blind men and an elephant”:The need for animals in research,drug safety studies,and understanding civilizational diseases  

作　　者：Savani Anbalagan 

机构地区：[1]Faculty of Biology,Institute of Molecular Biology and Biotechnology,Adam Mickiewicz University in Poznań,Poznań,Poland

出　　处：《Animal Models and Experimental Medicine》2023年第6期627-633,共7页动物模型与实验医学（英文）

基　　金：Narodowe Centrum Nauki,Grant/Award Number:SONATA 2021/43/D/NZ3/01798 and SONATA BIS 2020/38/E/NZ3/00090。

摘　　要：Animal-based research and drug safety studies are essential to understanding the mysteries of nature and the long-term survival of humans.Due to the rapid increase in the global human population,conflict-and economically driven human migration,tourism-related activities,densely populated metropolitan areas,and local policies,humans will be affected by a multitude of novel disease-causing microorganisms and civilizational diseases.Despite disparities among countries,recent and planned changes in regulations concerning animal research and drug safety studies could have detrimental effects on both the animal research community and nations lacking sufficient social support systems.Based on existing scientific literature,I argue that we need animal research encompassing aspects such as animal development,behavior,drug safety studies,and for the understanding of future civilizational diseases.Depending on the nature of the research questions and local challenges,a suitable animal model organism should be made mandatory.

关 键 词：animal model drug safety studies RESEARCH ZEBRAFISH 

分 类 号：R-3[医药卫生]