Anti-inflammatory and anti-cancer potential of pterostilbene:A review  

作　　者：Omchit Surien Siti Fathiah Masre Dayang Fredalina Basri Ahmad Rohi Ghazali 

机构地区：[1]Centre for Toxicology and Health Risk Studies(CORE),Faculty of Health Sciences,Universiti Kebangsaan Malaysia,50300,Kuala Lumpur,Malaysia [2]Centre of Diagnostic,Therapeutic&Investigative Studies(CODTIS),Faculty of Health Sciences,Universiti Kebangsaan Malaysia,50300,Kuala Lumpur,Malaysia

出　　处：《Asian Pacific Journal of Tropical Biomedicine》2023年第12期497-506,共10页亚太热带生物医学杂志（英文版）

基　　金：the Ministry of Higher Education(MOHE)Malaysia through the Fundamental Research Grant Scheme(FRGS)with grant number:FRGS/1/2019/SKK10/UKM/01/1.

摘　　要：Pterostilbene is a natural compound that can be found in various food plants such as blueberries,grapes,and peanuts.It has also been reported to be extracted from Pterocarpus indicus,a tree species native to India and Southeast Asia.Pterostilbene exhibits various pharmacological activities such as antioxidants,anti-proliferation,anti-microbial,and anti-inflammatory activities with favorable pharmacokinetic properties,such as high oral bioavailability and longer half-life.The anti-inflammatory effect of pterostilbene has been reported to contribute to its therapeutic effects in many chronic inflammatory diseases.Besides,pterostilbene has anti-cancer activity on various types of cancers due to its ability to induce cell cycle arrest and apoptosis.Hence,in this review,we discuss the anti-inflammatory and anti-cancer activities of pterostilbene in preclinical studies.

关 键 词：PTEROSTILBENE ANTI-CANCER NF-ΚB ANTI-INFLAMMATION Natural product Pterocarpus indicus 

分 类 号：R285[医药卫生—中药学]