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作 者:Zizhen Guo Lingling Ge Yuehua Li Yihui Gu Wei Wang Chengjiang Wei Bin Gu Qingfeng Li Zhichao Wang
出 处:《Chinese Journal of Plastic and Reconstructive Surgery》2023年第4期163-172,共10页
基 金:the National Natural Science Foundation of China(grant nos.82202470,82102344,and 82172228);Shanghai Rising Star Program supported by the Science and Technology Commission of Shanghai Municipality(grant no.20QA1405600);Natural Science Foundation of Shanghai(grant no.22ZR1422300);Innovative Research Team of High-Level Local Universities in Shanghai(grant no.SHSMU-ZDCX20210400);Clinical Research Plan of SHDC(grant no.SHDC2020CR1019B);Shanghai Clinical Research Center of Plastic and Reconstructive Surgery supported by(grant no.22MC1940300).
摘 要:Background:Melanocytic nevus is mainly treated by complete or partial removal.However,predicting the risk of malignant transformation of melanocytic nevi and which treatment patients should receive,surgical or nonsurgical management,to gain the best results and aesthetic outcomes is controversial.Methods:Global literature on melanocytic nevus treatment,published between 1997 and 2022,was scanned using the Web of Science Core Collection database.Microsoft Office Excel,CiteSpace V,VOSviewer,Scimago Graphica,Bibliometrix,and Biblioshiny packages in R were used for the bibliometric analysis to summarize the leading countries,institutions,professors,and research trends in this field.Results:This study included 1723 articles.Publications and citations exhibited positive trends over the past 20 years.The United States had the most productive organizations and publications in the comprehensive worldwide cooperation network,and China was recently one of the most active major participants.Professor Giovanni Pellacani,whose H-index,G-index,and M-index ranked first in this field,founded a virtual biopsy using reflectance confocal microscopy.In addition,Krengel and Kinsler contributed significantly to diagnosing and treating melanocytic nevi.The top 25 keywords in recent years were mostly about the mechanisms and risk factors for the malignant transformation of nevi.Conclusion:The future trend for melanocytic nevi treatment is to specify genotype-phenotype and genotypeoutcome correlations,choose proper therapy to reduce the risk of malignant transformation,and simultaneously achieve the best aesthetic outcomes.
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