清华大学实验动物中心小鼠自动饮水系统漏水情况统计分析  

Statistical Analysis of the Leakage Situation in the Automated Watering System for Mice in Tsinghua University Laboratory Animal Resources Center

作　　者：唐倩倩 张秀莉 常在[1] TANG Qianqian;ZHANG Xiui;CHANG Zai(SchoolofLifeSciences,TsinghuaUniversity,Beijing100084,China)

机构地区：[1]清华大学生命科学学院,北京100084

出　　处：《实验动物与比较医学》2024年第1期85-91,共7页Laboratory Animal and Comparative Medicine

摘　　要：目的统计清华大学实验动物中心小鼠自动饮水系统漏水情况,评估自动饮水设备安全性,为动物设施自动饮水系统的选用和使用维护管理提供参考。方法本文以清华大学实验动物中心二期动物设施南、北两个屏障饲养区的小鼠自动饮水系统为研究对象,分别进行了为期3年、1年半的漏水情况监测记录。通过统计分析监测期内两个屏障饲养区漏水事件发生案例,将漏水原因分为人员误操作、动物行为、异物阻塞、配件变形4种,计算南、北区自动饮水系统因前述4种漏水原因造成的总日漏水率,以及因设备自身质量问题即异物阻塞和配件变形两种漏水原因造成的日漏水率,并进一步对漏水原因以及漏水给设施带来的影响进行分析讨论。同时,统计在监测期末,未使用自动饮水的一期设施和使用自动饮水系统的二期设施的动物饲养量和饲养人员数量,计算两种饲养模式下人均负责笼位数的差异。结果监测期内两个区域共发生漏水52起,总日漏水率为0.00013%。其中,人员误操作导致的漏水有31起,约占漏水总发生量的60%,在加强培训、监督检查和有效提醒措施下,可降低人员误操作导致漏水的发生率;动物行为导致的漏水有2起;异物阻塞导致漏水0起;因设备质量原因导致的漏水有19起,日漏水率为0.00007%。根据清华大学实验动物中心的运行数据统计,使用自动饮水系统的二期设施人均负责笼位数为908笼,而未使用自动饮水系统的一期设施人均负责笼位数为570笼,在使用自动饮水的条件下人均负责笼位数增加约59%。结论清华大学实验动物中心自动饮水系统日漏水率远低于设备理论设计值0.003%,进一步证明了自动饮水系统的安全性和有效性。同时,自动饮水系统的使用可以大幅提升饲养工作效率,除购入自动饮水系统需投入采购成本外,饲养用工成本将随着工作效率的提升而不�Objective To calculate the leakage rate of the automated watering system in Tsinghua University Laboratory Animal Resources Center,to evaluate the safety of the system,and provide references for selection,maintenance,and management of automated watering systems in animal facilities.Methods This study investigated the automated watering system installed in South and North Barriers of Tsinghua University Laboratory Animal Resources Center(Phase II).Water leakage monitoring was conducted over two periods,one over a period of 3 years and the other over 1.5 years.The occurrence of water leakage events at the two barriers during the monitoring period was statistically analyzed,classifying the causes into four categories:mishandling by personnel,animal behavior,obstruction by foreign objects,and deformation of fittings.The total daily leakage rate due to these causes and the daily leakage rate caused by quality issues,i.e.obstruction by foreign objects and deformation of fittings were calculated.Further analysis and discussion focused on the causes of water leakage and its impact on the facilities.At the same time,the number of caretakers at the end of the monitoring period in the Phase I facility without automated watering system and the Phase II facility with automated watering system were counted.Finally the difference in the number of cages per capita under the two watering systems was calculated.Results A total of 52 water leakage incidents occurred in both areas during the monitoring period,with a total daily leakage rate of 0.00013%.Among them,31 were caused by personnel mishandling,accounting for approximately 60%of total leakages.Enhanced training,supervision,inspection,and effective reminder measures could reduce leakage caused by personnel mishandling.There were 2 cases of water leakages caused by animal behavior,0 leakage due to obstruction by foreign objects,and 19 leakages due to system quality issues,with a daily leakage rate of 0.00007%.According to the operation data of Tsinghua University Laboratory An

关 键 词：实验动物 动物设施 自动饮水 漏水率 小鼠 

分 类 号：R-332[医药卫生] G482[文化科学—教育学]