苯乳酸对雏鸡沙门氏菌感染模型的治疗  

Treatment of Phenyllactic Acid in a Model of Salmonella Infection in Chicks

作　　者：胡鹏程 张怀瑾 高阿波 魏怡 刘鼎阔 HU Pengcheng;ZHANG Huaijin;GAO A'bo;WEI Yi;LIU Dingkuo(Dingzheng Xinxing Biotechnology(Tianjin)Co.,Ltd.,Tianjin 300383,China;Tianjin Key Laboratory of Biological Feed Additives,Tianjin 300383,China;Tianjin Enterprise Technology Center,Tianjin 300383,China)

机构地区：[1]鼎正新兴生物技术(天津)有限公司,天津300383 [2]天津市生物饲料添加剂企业重点实验室,天津300383 [3]天津市企业技术中心,天津300383

出　　处：《现代畜牧科技》2024年第2期22-25,共4页Modern Animal Husbandry Science & Technology

摘　　要：为验证苯乳酸(PLA)对鸡白痢沙门氏菌的抑杀能力,利用活化的鸡白痢沙门氏菌对雏鸡灌胃,直至雏鸡排便出现白痢等典型感染症状,以此为标准确定鸡白痢沙门氏菌感染模型构建成功,然后进行治疗,发现苯乳酸干预后实验组鸡白痢沙门氏菌感染症状明显改观,相比阴性对照组半数致死,阳性对照组15%的死淘率,实验组死淘率仅为5%。因此苯乳酸可以取代硫酸新霉素等传统鸡白痢沙门氏菌敏感型抗生素,治疗禽类沙门氏菌感染引起的疾病。In order to verify the inhibition ability of PLA on Salmonella induced white dysentery,first of all,activated Salmonella was used to gavage chicks until typical infection symptoms such as white dysentery,appeared in chicks,and the model of Salmonella infection was successfully constructed as a standard,and then treated,and it was found that after PLA intervention,the symptoms of Salmonella infection in the experimental group were significantly improved,compared with half of the death in the negative control group,15%of the death rate of the positive control group,and only 5% of the death rate in the experimental group.Therefore,PLA can replace traditional antibiotics such as neomycin sulfate and other sensitive antibiotics for Salmonella in chickens to treat diseases caused by Salmonella avian infection.

关 键 词：雏鸡 沙门氏菌 替抗 抑菌 动物实验 

分 类 号：S858.31[农业科学—临床兽医学]